CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011133
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein dopey 
Protein Synonyms/Alias
  
Gene Name
 DOP1 
Gene Synonyms/Alias
 YDR141C; YD9302.17C 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
581NPSSILEKENIAERLubiquitination[1]
639IPESEELKGRSHISWubiquitination[1]
1302LISGKVSKTQFGEQKubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301
Functional Description
 Involved in cellular morphogenesis. Required for traffic between late Golgi and early endosomes, and for the normal structure and organization of the endoplasmic reticulum. 
Sequence Annotation
 MOD_RES 244 244 Phosphoserine.  
Keyword
 Complete proteome; Golgi apparatus; Membrane; Phosphoprotein; Protein transport; Reference proteome; Repeat; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1698 AA 
Protein Sequence
MSLPLKPLTI DSNNKQLDSK QKKFRANVER ALERFDSVTE WADYIASLGT LLKALQSWSP 60
KFQNVRYYVP SPYQVSRRLT SSLSPALPAG VHQKTLEVYT YIFEHIGLET LATECNIWIP 120
GILPLMTYAS MSVRSHLIEL YDNYILLLPQ TTLRLLIRPL ISSLLPGIDD ESNDFLPLTL 180
KLIETLQENL DDDSLFWQTL FLVMTANKGR RLGGLTWLTR KFPSLNAVPH LVNKIKMEAE 240
ENPSETETND SHLDRKKRKE EAFKVLLPAA KDLVTPEPGL LIRCLVGCLE DENDILIKRS 300
VLDLLLQRLR LDSPVLNVLI TSEDKKLLIM SCCRTTLSKD MSLNRRIWNW LLGPTAGGML 360
NNNGGNSMEY TTSVKSANEE SNVYFTKYGL SALLEGLSDL LSEEESVLTA FRISMAVMDR 420
WEIGSLVIPE LFIPLLYSSE KFKQNEQIMK TARTFFDNTE TNIIWGKLFQ ELEDIKNLKI 480
LDFVLTNFNI GNDEEIIVRH LPLILLTLLA LPSNDKDFDN IYKLQKFSLY NKLLNYIPER 540
ALLPLSHSKL KHDDEVSCEE LLAKIRGFYT NVSNPSSILE KENIAERLPP FTTEDLTFLI 600
ADLIQKKLLS SLWDLENINE SSKLFIAIFE KIPESEELKG RSHISWSDKK ITQSIFEAIP 660
RLCESNNDAK SEEIVGIVEI FGNYLYSRME FIESMKLLKV VMMAVWKSLK DPRHQILGVK 720
NLKTLNRFIP SKFIESALVY TFVEEEDISE RLSVLDLLWT QLDSDSNLIR RPLELILGEL 780
FDDQNPFYLT VSKWILSILN SGSASRLFYI LTDNILKVNR LEKERLDERD DLDMLTYEFQ 840
MLAYVLKTNN GRTRKVFSTE LTSIKSSTIW KNEDVSTYKS LLLVTLMRFL NIKSNTHAKS 900
IRSALILLDI LLDGTEQNFK DIVIFLLQMS SKYIAEEGIE PELIAVSLLD IVSKVLRLSH 960
DNGIKLDIFD DNAAHLKYID FLVTSVSNMK SPLIVTAYVK LLSESIVYFE NSIFRMILPL 1020
SASLVQCVQR LFLLEKREGG YYQPIALLLG GLEELLEISH GYLVTEEREG YFSGSNLKGD 1080
FIQSVVSNVF SSDSSNEESK IQGERDVILQ SFRQVISCCL DIWYWAHNIS CKSNDDSSLD 1140
ATNHNSYKFK FRSKKLLETL FLLEPLELLE NLISIRSDNT TVTLVHVLDG NKPAITIPHL 1200
LYGVIIRYNR TASVKFSNRD GSRSSTTKLT KGEPSMLKRL SGESIIAFLF NYVDSVENSA 1260
MEEFYGDFLL FFREVATNYN LYSDVSLSIL KLVALISGKV SKTQFGEQKR VRREISDVFF 1320
KYLPNAFINF TNLYRGHPDS FKDLEFVVWR VQYIVNDQIG GDKFNTTLAT IVNQCLTPYI 1380
KPKSEKTIPG YVLELAAVVS HLGSKVKSWR LLIAELFQND KKLSVIGSDQ TWEKIIYEWS 1440
IYPENKSKIL NDLLLEIGSK RSSVTPTLIT FNLGSDSEVE YKCQNLLKIS YLLMVSPNDA 1500
YLLHFSSLIS CIFHYLVSKD IKLKGSCWIL LRVLLLRFSE SHFNDYWSMI SYCLQTNLQE 1560
FYESLQIQSE VDPQTILQVC KTLDLLLLLN MEGFTSTNEW IFVIDTINCV YKTNSFVALV 1620
DEIAEFKDYE ITKTDDLELP TTLKDGLPLL RGIHKIERHT QLRSFFQNLS YLHYEKVYGL 1680
GSVDLYGCGE DLKKDILS 1698 
Gene Ontology
 GO:0005768; C:endosome; IDA:SGD.
 GO:0000139; C:Golgi membrane; IDA:HGNC.
 GO:0005739; C:mitochondrion; IDA:SGD.
 GO:0005802; C:trans-Golgi network; IDA:SGD.
 GO:0000902; P:cell morphogenesis; IMP:SGD.
 GO:0007029; P:endoplasmic reticulum organization; IMP:HGNC.
 GO:0006895; P:Golgi to endosome transport; IMP:HGNC.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW. 
Interpro
 IPR016024; ARM-type_fold.
 IPR007249; Dopey_N. 
Pfam
 PF04118; Dopey_N 
SMART
  
PROSITE
  
PRINTS