UniProt Accession

 ARGD_MYCS2; A0QYS9; I7FN58 

Genbank Protein ID

 CP000480; CP001663 

Genbank Nucleotide ID

 ABK75110.1; AFP40143.1 

Protein Name

 Acetylornithine aminotransferase 

Protein Synonyms/Alias

 ACOAT 

Gene Name

 argD 

Gene Synonyms/Alias

 MSMEG_3773; MSMEI_3684 

Created Date

 July 27, 2013 

Organism

 Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) 

NCBI Taxa ID

 246196 

Lysine Modification

Position	Peptide	Type	References
304	ARAGVLGKTLSHGIE	pupylation	[1]

Reference

 [1] Expansion of the mycobacterial "PUPylome".
 Watrous J, Burns K, Liu WT, Patel A, Hook V, Bafna V, Barry CE 3rd, Bark S, Dorrestein PC.
 Mol Biosyst. 2010 Feb;6(2):376-85. [PMID: 20094657] 

Functional Description

  

Sequence Annotation

 REGION 214 217 Pyridoxal phosphate binding (By
 BINDING 129 129 Pyridoxal phosphate; via carbonyl oxygen
 BINDING 132 132 N2-acetyl-L-ornithine (By similarity).
 BINDING 271 271 N2-acetyl-L-ornithine (By similarity).
 BINDING 272 272 Pyridoxal phosphate (By similarity).
 MOD_RES 243 243 N6-(pyridoxal phosphate)lysine (By
 CROSSLNK 304 304 Isoglutamyl lysine isopeptide (Lys-Gln)  

Keyword

 Amino-acid biosynthesis; Aminotransferase; Arginine biosynthesis; Complete proteome; Cytoplasm; Isopeptide bond; Pyridoxal phosphate; Reference proteome; Transferase; Ubl conjugation. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 390 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0003992; F:N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity; IEA:HAMAP.
 GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
 GO:0006526; P:arginine biosynthetic process; IEA:HAMAP. 

Interpro

 IPR005814; Aminotrans_3.
 IPR015424; PyrdxlP-dep_Trfase.
 IPR015421; PyrdxlP-dep_Trfase_major_sub1.
 IPR015422; PyrdxlP-dep_Trfase_major_sub2.
 IPR004636; Trfase_AcOrn/SuccOrn_fam. 

Pfam

 PF00202; Aminotran_3 

SMART

  

PROSITE

 PS00600; AA_TRANSFER_CLASS_3 

PRINTS