UniProt Accession

 SPRY3_HUMAN; Q8NCJ5; B9EG99; Q96SK5 

Genbank Protein ID

 AK027706; AK074694; CH471054; BC136312 

Genbank Nucleotide ID

 BAB55311.1; BAC11144.1; EAW96662.1; AAI36313.1 

Protein Name

 SPRY domain-containing protein 3 

Protein Synonyms/Alias

  

Gene Name

 SPRYD3 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
14	PRFVLMNKMDDLNLH	ubiquitination	[1, 2, 3]
240	LEYLGKGKSIVDVGL	ubiquitination	[2]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 

Functional Description

  

Sequence Annotation

 DOMAIN 17 204 B30.2/SPRY.  

Keyword

 3D-structure; Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 442 AA 

Protein Sequence

Gene Ontology

  

Interpro

 IPR001870; B30.2/SPRY.
 IPR008985; ConA-like_lec_gl_sf.
 IPR018355; SPla/RYanodine_receptor_subgr.
 IPR003877; SPRY_rcpt. 

Pfam

 PF00622; SPRY 

SMART

 SM00449; SPRY 

PROSITE

 PS50188; B302_SPRY 

PRINTS