UniProt Accession

 GATD_ECOLI; P0A9S3; P37190; P76410 

Genbank Protein ID

 X79837; U00096; AP009048 

Genbank Nucleotide ID

 CAA56231.1; AAC75152.1; BAA15954.1 

Protein Name

 Galactitol-1-phosphate 5-dehydrogenase 

Protein Synonyms/Alias

  

Gene Name

 gatD 

Gene Synonyms/Alias

 b2091; JW2075 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
23	ESVIPEIKHQDEVRV	acetylation	[1]
105	GFYSQCAKYDFIGSR	acetylation	[1]
124	FAEYIVVKRKNVFAL	acetylation	[1]
197	AIDISSEKLALAKSF	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 Converts galactitol 1-phosphate to tagatose 6-phosphate. 

Sequence Annotation

 METAL 38 38 Zinc 1; catalytic (By similarity).
 METAL 59 59 Zinc 1; catalytic (By similarity).
 METAL 89 89 Zinc 2 (By similarity).
 METAL 92 92 Zinc 2 (By similarity).
 METAL 95 95 Zinc 2 (By similarity).
 METAL 103 103 Zinc 2 (By similarity).
 METAL 144 144 Zinc 1; catalytic (By similarity).  

Keyword

 3D-structure; Complete proteome; Galactitol metabolism; Metal-binding; NAD; Oxidoreductase; Reference proteome; Zinc. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 346 AA 

Protein Sequence

Gene Ontology

 GO:0008868; F:galactitol-1-phosphate 5-dehydrogenase activity; IEA:EC.
 GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IDA:EcoCyc.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0019404; P:galactitol catabolic process; IMP:EcoCyc. 

Interpro

 IPR013149; ADH_C.
 IPR013154; ADH_GroES-like.
 IPR002085; ADH_SF_Zn-type.
 IPR002328; ADH_Zn_CS.
 IPR011032; GroES-like.
 IPR016040; NAD(P)-bd_dom. 

Pfam

 PF08240; ADH_N
 PF00107; ADH_zinc_N 

SMART

  

PROSITE

 PS00059; ADH_ZINC 

PRINTS