CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039154
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Slc25a12 
Protein Synonyms/Alias
  
Gene Name
 Slc25a12 
Gene Synonyms/Alias
 LOC100360985 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
51NDPNSNPKIVQLLAGacetylation[1]
165ARQAFALKDKSKSGMacetylation[1]
401LIGVAPEKAIKLTVNacetylation[1]
404VAPEKAIKLTVNDFVacetylation[1]
480LGLFGLYKGAKACFLacetylation[1]
576EGPSAFWKGTAARVFacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Calcium; Complete proteome; Membrane; Reference proteome; Repeat; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 675 AA 
Protein Sequence
VHTTKRGDPH ELRNIFLQYA STEVDGEHYM TPEDFVQRYL GLYNDPNSNP KIVQLLAGVA 60
DQTKDGLISY QEFLAFESVL CAPDSMFIVA FQLFDKSGNG EVTFENVKEI FGQTIIHHHI 120
PFNWDCEFIR LHFGHNRKKH LNYVEFTQFL QELQLEHARQ AFALKDKSKS GMISGLDFSD 180
VMVTIRSHML TPFVEENLVS AAGGSTSHQV SFSYFNAFNS LLNNMELVRK IYSTLAGTRK 240
DIEVTKEPLP RKCKALGSVA PLNTSLQLLG EKGVLYLRGL RLTLADIERI APLAEGALPY 300
NLAELQRQQS PGLGRPIWLQ IAESAYRFTL GSVAGAVGAT AVYPIDLVKT RMQNQRGTGS 360
VVGELMYKNS FDCFKKVLRY EGFFGLYRGL IPQLIGVAPE KAIKLTVNDF VRDKFTRRDG 420
SIPLPAEILA GGCAGGSQVI FTNPLEIVKI RLQVAGEITT GPRVSALNVL QDLGLFGLYK 480
GAKACFLRDI PFSAIYFPVY AHCKLLLADE NGHVGGINLL TAGAMAGVPA ASLVTPADVI 540
KTRLQVAARA GQTTYSGVID CFRKILREEG PSAFWKGTAA RVFRSSPQFG VTLVTYELLQ 600
RWFYIDFGGL KPSGSEPTPK SRIADLPPAN PDHIGGYRLA TATFAGIENK FGLYLPKFKS 660
PGVAAAQPKV AAAAQ 675 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005743; C:mitochondrial inner membrane; IEA:Compara.
 GO:0005509; F:calcium ion binding; IEA:Compara.
 GO:0015183; F:L-aspartate transmembrane transporter activity; IEA:Compara.
 GO:0005313; F:L-glutamate transmembrane transporter activity; IEA:Compara.
 GO:0043490; P:malate-aspartate shuttle; IEA:Compara.
 GO:0051592; P:response to calcium ion; IEA:Compara. 
Interpro
 IPR011992; EF-hand-like_dom.
 IPR018247; EF_Hand_1_Ca_BS.
 IPR002048; EF_hand_dom.
 IPR002067; Mit_carrier.
 IPR018108; Mitochondrial_sb/sol_carrier.
 IPR023395; Mt_carrier_dom. 
Pfam
 PF13405; EF_hand_4
 PF00153; Mito_carr 
SMART
 SM00054; EFh 
PROSITE
 PS00018; EF_HAND_1
 PS50222; EF_HAND_2
 PS50920; SOLCAR 
PRINTS
 PR00926; MITOCARRIER.