CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-012565
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein phosphatase 1 regulatory subunit 7 
Protein Synonyms/Alias
 Protein phosphatase 1 regulatory subunit 22 
Gene Name
 PPP1R7 
Gene Synonyms/Alias
 SDS22 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
174LESLFLGKNKITKLQubiquitination[1]
201MQSNRLTKIEGLQNLubiquitination[1]
Reference
 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661
Functional Description
 Regulatory subunit of protein phosphatase 1 (By similarity). 
Sequence Annotation
 REPEAT 77 98 LRR 1.
 REPEAT 99 120 LRR 2.
 REPEAT 121 142 LRR 3.
 REPEAT 143 164 LRR 4.
 REPEAT 165 186 LRR 5.
 REPEAT 187 208 LRR 6.
 REPEAT 209 230 LRR 7.
 REPEAT 231 252 LRR 8.
 REPEAT 253 274 LRR 9.
 REPEAT 275 296 LRR 10.
 REPEAT 297 318 LRR 11.
 DOMAIN 331 360 LRRCT.
 MOD_RES 2 2 N-acetylalanine.
 MOD_RES 12 12 Phosphoserine.
 MOD_RES 24 24 Phosphoserine.
 MOD_RES 27 27 Phosphoserine.
 MOD_RES 44 44 Phosphoserine.
 MOD_RES 47 47 Phosphoserine.  
Keyword
 Acetylation; Alternative splicing; Complete proteome; Leucine-rich repeat; Nucleus; Phosphoprotein; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 360 AA 
Protein Sequence
MAAERGAGQQ QSQEMMEEEH ELPVDMETIN LDRDAEDVDL NHYRIGKIEG FEVLKKVKTL 60
CLRQNLIKCI ENLEELQSLR ELDLYDNQIK KIENLEALTE LEILDISFNL LRNIEGVDKL 120
TRLKKLFLVN NKISKIENLS NLHQLQMLEL GSNRIRAIEN IDTLTNLESL FLGKNKITKL 180
QNLDALTNLT VLSMQSNRLT KIEGLQNLVN LRELYLSHNG IEVIEGLENN NKLTMLDIAS 240
NRIKKIENIS HLTELQEFWM NDNLLESWSD LDELKGARSL ETVYLERNPL QKDPQYRRKV 300
MLALPSVRQI DATFVRF 317 
Gene Ontology
 GO:0005737; C:cytoplasm; TAS:ProtInc.
 GO:0005634; C:nucleus; TAS:ProtInc.
 GO:0008599; F:protein phosphatase type 1 regulator activity; TAS:ProtInc. 
Interpro
 IPR001611; Leu-rich_rpt.
 IPR025875; Leu-rich_rpt_4.
 IPR003603; U2A'_phosphoprotein32A_C. 
Pfam
 PF12799; LRR_4 
SMART
 SM00446; LRRcap 
PROSITE
 PS51450; LRR 
PRINTS