UniProt Accession

 RAB13_HUMAN; P51153; A8K6B5; D3DV67; Q5U0A6; Q6GPG6; Q96GU4 

Genbank Protein ID

 X75593; AY423722; AF498948; AK291580; BT019700; BT019701; AL358472; CH471121; CH471121; BC000799; BC009227; BC073168 

Genbank Nucleotide ID

 CAA53266.1; AAS00485.1; AAM21096.1; BAF84269.1; AAV38506.1; AAV38507.1; CAI14031.1; EAW53249.1; EAW53250.1; AAH00799.1; AAH09227.2; AAH73168.2 

Protein Name

 Ras-related protein Rab-13 

Protein Synonyms/Alias

 Cell growth-inhibiting gene 4 protein 

Gene Name

 RAB13 

Gene Synonyms/Alias

 GIG4 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
3	*****MAKAYDHLFK	acetylation	[1]
71	TAGQERFKTITTAYY	ubiquitination	[2]
104	ENIQNWMKSIKENAS	ubiquitination	[3]
107	QNWMKSIKENASAGV	ubiquitination	[3]
195	DLKTCDKKNTNKCSL	ubiquitination	[2]

Reference

 [1] Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.
 Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, Baskcomb L, Mann M, Jackson SP, Choudhary C.
 Mol Cell. 2012 Apr 27;46(2):212-25. [PMID: 22424773]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

 Could participate in polarized transport, in the assembly and/or the activity of tight junctions. 

Sequence Annotation

 NP_BIND 15 22 GTP (By similarity).
 NP_BIND 63 67 GTP (By similarity).
 NP_BIND 121 124 GTP (By similarity).
 MOTIF 37 45 Effector region (By similarity).
 MOD_RES 178 178 Phosphoserine.
 MOD_RES 200 200 Cysteine methyl ester (Potential).
 LIPID 200 200 S-geranylgeranyl cysteine (By  

Keyword

 Cell junction; Cell membrane; Complete proteome; Cytoplasmic vesicle; GTP-binding; Lipoprotein; Membrane; Methylation; Nucleotide-binding; Phosphoprotein; Prenylation; Protein transport; Reference proteome; Tight junction; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 203 AA 

Protein Sequence

Gene Ontology

 GO:0030659; C:cytoplasmic vesicle membrane; TAS:Reactome.
 GO:0005794; C:Golgi apparatus; IEA:Compara.
 GO:0005886; C:plasma membrane; IDA:HPA.
 GO:0005923; C:tight junction; TAS:ProtInc.
 GO:0005525; F:GTP binding; IDA:UniProtKB.
 GO:0003924; F:GTPase activity; EXP:Reactome.
 GO:0007155; P:cell adhesion; TAS:ProtInc.
 GO:0016044; P:cellular membrane organization; TAS:Reactome.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW.
 GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
 GO:0016192; P:vesicle-mediated transport; TAS:ProtInc. 

Interpro

 IPR027417; P-loop_NTPase.
 IPR005225; Small_GTP-bd_dom.
 IPR001806; Small_GTPase.
 IPR003579; Small_GTPase_Rab_type. 

Pfam

 PF00071; Ras 

SMART

 SM00175; RAB 

PROSITE

 PS51419; RAB 

PRINTS

 PR00449; RASTRNSFRMNG.