CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036867
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 G-protein-coupled receptor 56 
Protein Synonyms/Alias
  
Gene Name
 GPR56 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
116GRSGEAEKRLLLVDFubiquitination[1]
132SQALFQDKNSSQVLGubiquitination[1]
503RGGPSPLKSNSDSARubiquitination[1]
Reference
 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661
Functional Description
  
Sequence Annotation
  
Keyword
 Cell membrane; Complete proteome; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 523 AA 
Protein Sequence
MTPQSLLQTT LFLLSLLFLV QGAHGRGHRE DFRFCSQQLQ SLESKLTSVR FMGDMVSFEE 60
DRINATVWKL QPTAGLQDLH IHSRQEEEQS EIMEYSVLLP RTLFQRTKGR SGEAEKRLLL 120
VDFSSQALFQ DKNSSQVLGE KVLGIVVQNT KVANLTEPVV LTFQHQLQPK NVTLQCVFWV 180
EDPTLSSPGH WSSAGCETVR RETQTSCFCN HLTYFAVLMV SSVEVDAVHK HYLSLLSYVG 240
CVVSALACLV TIAAYLCSRV PLPCRRKPRD YTIKVHMNLL LAVFLLDTSF LLSEPVALTG 300
SEAGCRASAI FLHFSLLTCL SWMGLEGYNL YRLVVEVFGT YVPGYLLKLS AMGWGFPIFL 360
VTLVALVDVD NYGPIILAVH RTPEGVIYPS MCWIRDSLVS YITNLGLFSL VFLFNMAMLA 420
TMVVQILRLR PHTQKWSHVL TLLGLSLVLG LPWALIFFSF ASGTFQLVVL YLFSIITSFQ 480
GFLIFIWYWS MRLQARGGPS PLKSNSDSAR LPISSGSTSS SRI 523 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
 GO:0004930; F:G-protein coupled receptor activity; IEA:InterPro.
 GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro. 
Interpro
 IPR017981; GPCR_2-like.
 IPR003910; GPCR_2_orphan_rcpt_GPR56.
 IPR000832; GPCR_2_secretin-like.
 IPR000203; GPS_dom. 
Pfam
 PF00002; 7tm_2
 PF01825; GPS 
SMART
 SM00303; GPS 
PROSITE
 PS50261; G_PROTEIN_RECEP_F2_4
 PS50221; GPS 
PRINTS
 PR00249; GPCRSECRETIN.
 PR01422; GPR56ORPHANR.