CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-018433
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Methionine import ATP-binding protein MetN 1 
Protein Synonyms/Alias
  
Gene Name
 metN1 
Gene Synonyms/Alias
 STM0247 
Created Date
 July 27, 2013 
Organism
 Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) 
NCBI Taxa ID
 99287 
Lysine Modification
Position
Peptide
Type
References
146ANLSGGQKQRVAIARacetylation[1]
Reference
 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 
Functional Description
 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity). 
Sequence Annotation
 DOMAIN 2 241 ABC transporter.
 NP_BIND 38 45 ATP (Potential).  
Keyword
 Amino-acid transport; ATP-binding; Cell inner membrane; Cell membrane; Complete proteome; Hydrolase; Membrane; Nucleotide-binding; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 343 AA 
Protein Sequence
MIKLSNITKV FQQGTRTIQA LNNVSLHVPA GQIYGVIGAS GAGKSTLIRC VNLLERPTEG 60
SVQVGGQELT TLSESELTKA RRQIGMIFQH FNLLSSRTVF GNVALPLELD NTPKEEIKRR 120
VTELLDLVGL GDKHDSYPAN LSGGQKQRVA IARALASNPK VLLCDEATSA LDPATTRSIL 180
ELLKDINRRL GLTILLITHE MDVVKRICDC VAVISNGELI EQDTVSEVFS HPKTPLAQKF 240
IQSTLHLDIP EDYQARLKAS PETDSVPMLR MEFTGQSVDA PLLSETARRF NVNNNIISAQ 300
MDYAGGVKFG IMLTEMHGTQ EETQAAIAWL QDHHVKVEVL GYV 343 
Gene Ontology
 GO:0009276; C:Gram-negative-bacterium-type cell wall; IEA:InterPro.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0016887; F:ATPase activity; IEA:InterPro.
 GO:0048474; F:D-methionine transmembrane transporter activity; IEA:InterPro.
 GO:0006200; P:ATP catabolic process; IEA:GOC. 
Interpro
 IPR003593; AAA+_ATPase.
 IPR026253; ABC_MetN.
 IPR012692; ABC_MetN_proteobac.
 IPR003439; ABC_transporter-like.
 IPR017871; ABC_transporter_CS.
 IPR017908; ABC_transprt_methionine_MetN_C.
 IPR018449; NIL_domain.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00005; ABC_tran
 PF09383; NIL 
SMART
 SM00382; AAA
 SM00930; NIL 
PROSITE
 PS00211; ABC_TRANSPORTER_1
 PS50893; ABC_TRANSPORTER_2
 PS51264; METN 
PRINTS