UniProt Accession

 TPM1_YEAST; P17536; D6W1A0; Q45TY1 

Genbank Protein ID

 M25501; DQ115393; X86470; Z71355; AY692838; BK006947 

Genbank Nucleotide ID

 AAA35174.1; AAZ22529.1; CAA60179.1; CAA95953.1; AAT92857.1; DAA10466.1 

Protein Name

 Tropomyosin-1 

Protein Synonyms/Alias

  

Gene Name

 TPM1 

Gene Synonyms/Alias

 YNL079C; N2332 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
12	REKLSNLKLEAESWQ	acetylation	[1]
26	QEKYEELKEKNKDLE	acetylation	[1]
30	EELKEKNKDLEQENV	acetylation	[1]
39	LEQENVEKENQIKSL	ubiquitination	[2]
44	VEKENQIKSLTVKNQ	acetylation	[1]
59	QLEDEIEKLEAGLSD	acetylation	[1]
59	QLEDEIEKLEAGLSD	ubiquitination	[2, 3]
77	TEQDNVEKENQIKSL	ubiquitination	[3]
125	NNDNFSKKNQQLEED	ubiquitination	[3]
187	VKYEDAKKELDEIAA	ubiquitination	[2]

Reference

 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919]
 [2] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047]
 [3] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 

Functional Description

  

Sequence Annotation

 MOD_RES 195 195 Phosphoserine.  

Keyword

 Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Phosphoprotein; Reference proteome; Repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 199 AA 

Protein Sequence

Gene Ontology

 GO:0032432; C:actin filament bundle; IDA:SGD.
 GO:0000142; C:cellular bud neck contractile ring; IDA:SGD.
 GO:0003786; F:actin lateral binding; TAS:SGD.
 GO:0051017; P:actin filament bundle assembly; IGI:SGD.
 GO:0008154; P:actin polymerization or depolymerization; TAS:SGD.
 GO:0007118; P:budding cell apical bud growth; TAS:SGD.
 GO:0007119; P:budding cell isotropic bud growth; TAS:SGD.
 GO:0030010; P:establishment of cell polarity; TAS:SGD.
 GO:0006887; P:exocytosis; TAS:SGD.
 GO:0008298; P:intracellular mRNA localization; TAS:SGD.
 GO:0000001; P:mitochondrion inheritance; TAS:SGD.
 GO:0007124; P:pseudohyphal growth; IMP:SGD.
 GO:0000011; P:vacuole inheritance; TAS:SGD. 

Interpro

 IPR000533; Tropomyosin. 

Pfam

 PF12718; Tropomyosin_1 

SMART

  

PROSITE

  

PRINTS