UniProt Accession

 PSME2_BOVIN; Q5E9G3; Q3T038; Q9TR87; Q9TR88; Q9TR89; Q9TR90 

Genbank Protein ID

 BT020957; BC102583 

Genbank Nucleotide ID

 AAX08974.1; AAI02584.1 

Protein Name

 Proteasome activator complex subunit 2 

Protein Synonyms/Alias

 Proteasome activator 28 subunit beta; PA28b; PA28beta 

Gene Name

 PSME2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Bos taurus (Bovine) 

NCBI Taxa ID

 9913 

Lysine Modification

Position	Peptide	Type	References
166	AFQTTISKYFSERGD	ubiquitination	[1]

Reference

 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 

Functional Description

 Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome. 

Sequence Annotation

 MOD_RES 2 2 N-acetylalanine (By similarity).
 MOD_RES 10 10 Phosphoserine (By similarity).  

Keyword

 Acetylation; Complete proteome; Direct protein sequencing; Phosphoprotein; Proteasome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 239 AA 

Protein Sequence

Gene Ontology

 GO:0008537; C:proteasome activator complex; IEA:InterPro. 

Interpro

 IPR003185; Proteasome_activ_REG_asu.
 IPR009077; Proteasome_activ_REG_asu/bsu.
 IPR003186; Proteasome_activ_REG_bsu. 

Pfam

 PF02251; PA28_alpha
 PF02252; PA28_beta 

SMART

  

PROSITE

  

PRINTS