UniProt Accession

 AT1B2_HUMAN; P14415; A0AV17; A8K278; D3DTQ2; O60444 

Genbank Protein ID

 M81181; U45945; AF007876; AK290143; CH471108; BC126175 

Genbank Nucleotide ID

 AAA51805.1; AAC50873.1; AAC39686.1; BAF82832.1; EAW90148.1; AAI26176.1 

Protein Name

 Sodium/potassium-transporting ATPase subunit beta-2 

Protein Synonyms/Alias

 Adhesion molecule in glia; AMOG; Sodium/potassium-dependent ATPase subunit beta-2 

Gene Name

 ATP1B2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
147	NGVLNYPKRACQFNR	ubiquitination	[1]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

 This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-2 subunit is not known. 

Sequence Annotation

 REGION 193 290 immunoglobulin-like.
 CARBOHYD 96 96 N-linked (GlcNAc...) (Potential).
 CARBOHYD 118 118 N-linked (GlcNAc...) (Potential).
 CARBOHYD 153 153 N-linked (GlcNAc...) (Potential).
 CARBOHYD 159 159 N-linked (GlcNAc...) (Potential).
 CARBOHYD 193 193 N-linked (GlcNAc...) (Potential).
 CARBOHYD 197 197 N-linked (GlcNAc...) (Potential).
 CARBOHYD 238 238 N-linked (GlcNAc...).
 CARBOHYD 250 250 N-linked (GlcNAc...) (Potential).
 DISULFID 129 150 By similarity.
 DISULFID 160 177 By similarity.
 DISULFID 200 261 By similarity.  

Keyword

 Cell adhesion; Cell membrane; Complete proteome; Disulfide bond; Glycoprotein; Ion transport; Membrane; Polymorphism; Potassium; Potassium transport; Reference proteome; Signal-anchor; Sodium; Sodium transport; Sodium/potassium transport; Transmembrane; Transmembrane helix; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 290 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0005886; C:plasma membrane; TAS:Reactome.
 GO:0005890; C:sodium:potassium-exchanging ATPase complex; IEA:InterPro.
 GO:0005391; F:sodium:potassium-exchanging ATPase activity; TAS:ProtInc.
 GO:0007596; P:blood coagulation; TAS:Reactome.
 GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
 GO:0050900; P:leukocyte migration; TAS:Reactome. 

Interpro

 IPR000402; Na/K_ATPase_sub_beta. 

Pfam

 PF00287; Na_K-ATPase 

SMART

  

PROSITE

 PS00390; ATPASE_NA_K_BETA_1
 PS00391; ATPASE_NA_K_BETA_2 

PRINTS