CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026351
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein Rac2 
Protein Synonyms/Alias
 Ras-related C3 botulinum toxin substrate 2 (Rho family, small GTP binding protein Rac2) 
Gene Name
 Rac2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
123KLDLRDDKDTIEKLKacetylation[1]
123KLDLRDDKDTIEKLKubiquitination[2]
128DDKDTIEKLKEKKLAubiquitination[2]
147PQGLALAKDIDSVKYacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; GTP-binding; Membrane; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 192 AA 
Protein Sequence
MQAIKCVVVG DGAVGKTCLL ISYTTNAFPG EYIPTVFDNY SANVMVDSKP VNLGLWDTAG 60
QEDYDRLRPL SYPQTDVFLI CFSLVSPASY ENVRAKWFPE VRHHCPSTPI ILVGTKLDLR 120
DDKDTIEKLK EKKLAPITYP QGLALAKDID SVKYLECSAL TQRGLKTVFD EAIRAVLCPQ 180
PTRQQKRPCS LL 192 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0016020; C:membrane; IEA:UniProtKB-KW.
 GO:0005635; C:nuclear envelope; IEA:Compara.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0003924; F:GTPase activity; IEA:Compara.
 GO:0030036; P:actin cytoskeleton organization; IDA:RGD.
 GO:0045453; P:bone resorption; IDA:RGD.
 GO:0030031; P:cell projection assembly; IEA:Compara.
 GO:0006935; P:chemotaxis; IEA:Compara.
 GO:0008284; P:positive regulation of cell proliferation; IEA:Compara.
 GO:0060263; P:regulation of respiratory burst; IEA:Compara.
 GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. 
Interpro
 IPR027417; P-loop_NTPase.
 IPR005225; Small_GTP-bd_dom.
 IPR001806; Small_GTPase.
 IPR003578; Small_GTPase_Rho. 
Pfam
 PF00071; Ras 
SMART
 SM00174; RHO 
PROSITE
 PS51420; RHO 
PRINTS
 PR00449; RASTRNSFRMNG.