| Tag | Content |
|---|
| CPLM ID | CPLM-018361 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Ankyrin repeat and SOCS box protein 13 |
Protein Synonyms/Alias | ASB-13 |
Gene Name | ASB13 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 216 | YARDNRGKKPSDYTW | ubiquitination | [1] | | 261 | TGVRGLEKIAKLNIP | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). |
Sequence Annotation | REPEAT 18 47 ANK 1.
REPEAT 51 80 ANK 2.
REPEAT 84 113 ANK 3.
REPEAT 116 145 ANK 4.
REPEAT 149 178 ANK 5.
REPEAT 181 210 ANK 6.
DOMAIN 229 278 SOCS box. |
Keyword | Alternative splicing; ANK repeat; Complete proteome; Reference proteome; Repeat; Ubl conjugation pathway. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 278 AA |
Protein Sequence | MEPRAADGCF LGDVGFWVER TPVHEAAQRG ESLQLQQLIE SGACVNQVTV DSITPLHAAS 60
LQGQARCVQL LLAAGAQVDA RNIDGSTPLC DACASGSIEC VKLLLSYGAK VNPPLYTASP 120
LHEACMSGSS ECVRLLIDVG ANLEAHDCHF GTPLHVACAR EHLDCVKVLL NAGANVNAAK 180
LHETALHHAA KVKNVDLIEM LIEFGGNIYA RDNRGKKPSD YTWSSSAPAK CFEYYEKTPL 240
TLSQLCRVNL RKATGVRGLE KIAKLNIPPR LIDYLSYN 278 |
Gene Ontology | GO:0035556; P:intracellular signal transduction; IEA:InterPro. GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |