CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011707
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Secernin-3 
Protein Synonyms/Alias
  
Gene Name
 SCRN3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
25DNRIIFGKNSDRLYDubiquitination[1]
398NKHLDVEKIVNLFPQubiquitination[2, 3]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [3] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789
Functional Description
  
Sequence Annotation
 ACT_SITE 6 6 Potential.  
Keyword
 Alternative splicing; Complete proteome; Polymorphism; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 424 AA 
Protein Sequence
MEPFSCDTFV ALPPATVDNR IIFGKNSDRL YDEVQEVVYF PAVVHDNLGE RLKCTYIEID 60
QVPETYAVVL SRPAWLWGAE MGANEHGVCI GNEAVWGREE VCDEEALLGM DLVRLGLERA 120
DTAEKALNVI VDLLEKYGQG GNCTEGRMVF SYHNSFLIAD RNEAWILETA GKYWAAEKVQ 180
EGVRNISNQL SITTKIAREH PDMRNYAKRK GWWDGKKEFD FAAAYSYLDT AKMMTSSGRY 240
CEGYKLLNKH KGNITFETMM EILRDKPSGI NMEGEFLTTA SMVSILPQDS SLPCIHFFTG 300
TPDPERSVFK PFIFVPHISQ LLDTSSPTFE LEDLVKKKSH FKPDRRHPLY QKHQQALEVV 360
NNNEEKAKIM LDNMRKLEKE LFREMESILQ NKHLDVEKIV NLFPQCTKDE IQIYQSNLSV 420
KVSS 424 
Gene Ontology
 GO:0016805; F:dipeptidase activity; IEA:InterPro.
 GO:0006508; P:proteolysis; IEA:InterPro. 
Interpro
 IPR005322; Peptidase_C69. 
Pfam
 PF03577; Peptidase_C69 
SMART
  
PROSITE
  
PRINTS