CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037764
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 7-dehydrocholesterol reductase 
Protein Synonyms/Alias
  
Gene Name
 DHCR7 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
199EFNPRIGKWFDFKLFubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 258 AA 
Protein Sequence
MAAKSQPNIP KAKSLDGVTN DRTASQGQWG RACCALTGPV VDIVTGHARL SDIWAKTPPI 60
TRKAAQLYTL WVTFQVLLYT SLPDFCHKFL PGYVGGIQEG AVTPAGVVNK YQINGLQAWL 120
LTHLLWFANA HLLSWFSPTI IFDNWIPLLW CANILGYAVS TFAMVKGYFF PTSARDCKFT 180
GNFFYNYMMG IEFNPRIGKW FDFKLFFNGR PGIVAWTLIN LSFAAKQREL HSHVTNAMVL 240
VNVLQAIYVI DFFWNETW 258 
Gene Ontology
 GO:0016020; C:membrane; IEA:InterPro.
 GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro. 
Interpro
 IPR001171; Ergosterol_biosynth_ERG4_ERG24.
 IPR018083; Sterol_reductase_CS. 
Pfam
 PF01222; ERG4_ERG24 
SMART
  
PROSITE
 PS01017; STEROL_REDUCT_1 
PRINTS