| Tag | Content |
|---|
| CPLM ID | CPLM-016480 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Ankyrin repeat and sterile alpha motif domain-containing protein 1B |
Protein Synonyms/Alias | Amyloid-beta protein intracellular domain-associated protein 1; AIDA-1; E2A-PBX1-associated protein; EB-1 |
Gene Name | Anks1b |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 1072 | YLGSMLIKELRGTES | ubiquitination | [1] | | 1114 | SVSYKGVKFIDAANK | ubiquitination | [1] | | 1231 | QIDPSEQKTLANLPW | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Isoform 2 may participate in the regulation of nucleoplasmic coilin protein interactions in neuronal and transformed cells (By similarity). |
Sequence Annotation | REPEAT 2 31 ANK 1.
REPEAT 58 87 ANK 2.
REPEAT 91 120 ANK 3.
REPEAT 127 156 ANK 4.
REPEAT 160 189 ANK 5.
REPEAT 193 222 ANK 6.
REPEAT 225 254 ANK 7.
DOMAIN 809 875 SAM 1.
DOMAIN 883 948 SAM 2.
DOMAIN 1055 1212 PID.
MOTIF 934 934 Nuclear localization signal (By
MOD_RES 900 900 Phosphotyrosine. |
Keyword | Alternative splicing; ANK repeat; Cell junction; Cell membrane; Cell projection; Complete proteome; Cytoplasm; Membrane; Nucleus; Phosphoprotein; Postsynaptic cell membrane; Reference proteome; Repeat; Synapse. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1259 AA |
Protein Sequence | MGKDQELLEA ARTGNVALVE KLLSGRKGGI LGGGSGPLPL SNLLSIWRGP NVNCTDSSGY 60
TALHHAALNG HKDIVLKLLQ YEASTNVADN KGYFPIHLAA WKGDVEIVKI LIHHGPSHSR 120
VNEQNNENET ALHCAAQYGH SEVVAVLLEE LTDPTIRNSK LETPLDLAAL YGRLRVVKMI 180
ISAHPNLMSC NTRKHTPLHL AARNGHKAVV QVLLEAGMDV SCQTEKGSAL HEAALFGKVD 240
VVRVLLETGI DANIKDSLGR TVLDILKEHP SQKSLQIATL LQDYLEGAGR SAAVLEEHAQ 300
EDTAQETHLS SPAESPQKTK SETVTGELSK LLDEIKLCQE KDYSFEDLCH TISDHYLDNL 360
SKISEEELGK NGSQSVRTSS TINLSPGEVE DEEEDPNSCG PTGLWEALTP CNGCRNLGFP 420
MLAQESYPKK RNFPMEMEPS ASLDTFPSEN ENFLCELVDT AVTKKPCSLE IARAPSPRTD 480
NASEVAITAP GTSHHRNSST GPTPDCSPPS PDTALKNIVK VIRPQPKQRT SIVSSLDFQR 540
MNHNQEYFEI STSTGCTSFT SSPAASPPTS SVETTEVKNE GAEHADDLSQ QEDDEPPKEY 600
DAGQFAGLLH GSSPACESPE NPFHLYGKRN TCEDGPDEAS LANSPLPFKQ TPIENNPEPS 660
VKKVKPKVVS RTIFHKRNHQ LENHTIVGTR MSRSGSRNGD QWGVNPGGFV ERACTLGRIR 720
SLPKALIDMH LSKNVSKSDS DLIAYPSKDK ARVNWSKSST AERSSKDNSE RTPSFTSEWE 780
EIDKIMNSID VGINSELEGM NGETTRPRCP VQTVGQWLES IGLPQYENHL MANGFDSVQF 840
MGSNVMEDQD LLEIGILNSG HRQRILQAIQ LLPKMRPIGH DGYHPTSVAE WLDSIELGDY 900
TKAFLINGYT SMDLLKKIWE LELINVLKIS LIGHRKRILA SLGDRLHDDP PQKPPRSITL 960
REPSGNHTPP QLSPSLSQST YTTGGSLDVP HIIMQGDARR RRNENYFDDI PRSKLERQMA 1020
QTGDWGEPSI TLRPPNEATA STPVQYWQHH PEKLIFQSCD YKAFYLGSML IKELRGTEST 1080
QDACAKMRAN CRKSTEQMKK VPTIILSVSY KGVKFIDAAN KNIIAEHEIR NISCAAQDPE 1140
DLSTFAYITK DLKSNHHYCH VFTAFDVNLA YEIILTLGQA FEVAYQLALQ ARKGGHSSTL 1200
PESFENKPSK PIPKPRVSIR KSVQIDPSEQ KTLANLPWIV EPGQEAKRGI NTKYETTIF 1259 |
Gene Ontology | GO:0030054; C:cell junction; IEA:UniProtKB-KW. GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0005886; C:plasma membrane; IEA:UniProtKB-KW. GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell. GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |