CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036946
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Intraflagellar transport protein 122 homolog 
Protein Synonyms/Alias
  
Gene Name
 IFT122 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
63VYCVAYAKDGKRFASubiquitination[1]
75FASGSADKSVIIWTSubiquitination[1]
83SVIIWTSKLEGILKYubiquitination[1]
655GLDFETAKKAFIRVQubiquitination[2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Repeat; WD repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1234 AA 
Protein Sequence
MRAVLTWRDK AEHCINDIAF KPDGTQLILA AGSRLLVYDT SDGTLLQPLK GHKDTVYCVA 60
YAKDGKRFAS GSADKSVIIW TSKLEGILKY TSWSVMSSLH LHLPFLGLHK TVRVTATDKA 120
PKGQGGRIDC LRPSVQNQPG QKHNDAIQCV SYNPITHQLA SCSSSDFGLW SPEQKSVSKH 180
KSSSKIICCS WTNDGQYLAL GMFNGIISIR NKNGEEKVKI ERPGGSLSPI WSICWNPSRE 240
ERNDILAVAD WGQKVSFYQL SGKQIGKDRA LNFDPCCISY FTKGEYILLG GSDKQVSLFT 300
KDGVRLGTVG EQNSWVWTCQ AKPDSNYVVV GCQDGTISFY QLIFSTVHGL YKDRYAYRDS 360
MTDVIVQHLI TEQKVRIKCK ELVKKIAIYR NRLAIQLPEK ILIYELYSED LSDMHYRVKE 420
KIIKKFECNL LVVCANHIIL CQEKRLQCLS FSGVKEREWQ MESLIRYIKV IGGPPGREGL 480
LVGLKNGQIL KIFVDNLFAI VLLKQATAVR CLDMSASRKK LAVVDENDTC LVYDIDTKEL 540
LFQEPNANSV AWNTQCEDML CFSGGGYLNI KASTFPVHRQ KLQGFVVGYN GSKIFCLHVF 600
SISAVEVPQS APMYQYLDRK LFKEAYQIAC LGVTDTDWRE LAMEALEGLD FETAKKAFIR 660
VQDLRYLELI SSIEERKKRG ETNNDLFLAD VFSYQGKFHE AAKLYKRSGH ENLALEMYTD 720
LCMFEYAKDF LGSGDPKETK MLITKQADWA RNIKEPKAAV EMYISAGEHV KAIEICGDHG 780
WVDMLIDIAR KLDKAEREPL LLCATYLKKL DSPGYAAETY LKMGDLKSLV QLHVETQRWD 840
EAFALGEKHP EFKDDIYMPY AQWLAENDRF EEAQKAFHKA GRQREAVQVL EQLTNNAVAE 900
SRFNDAAYYY WMLSMQCLDI AQADPAQKDT MLGKFYHFQR LAELYHGYHA IHRHTEDPFS 960
VHRPETLFNI SRFLLHSLPK DTPSGISKVK ILFTLAKQSK ALGAYRLARH AYDKLRGLYI 1020
PARFQKSIEL GTLTIRAKPF HDSEELVPLC YRCSTNNPLL NNLGNVCINC RQPFIFSASS 1080
YDVLHLVEFY LEEGITDEEA ISLIDLEVLR PKRDDRQLEI ANNSSQILRL VETKDSIGDE 1140
DPFTAKLSFE QGGSEFVPVV VSRLVLRSMS RRDVLIKRWP PPLRWQYFRS LLPDASITMC 1200
PSCFQMFHSE DYELLVLQHG CCPYCRRCKD DPGP 1234 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:HPA. 
Interpro
 IPR011990; TPR-like_helical.
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR017986; WD40_repeat_dom. 
Pfam
 PF00400; WD40 
SMART
 SM00320; WD40 
PROSITE
 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 
PRINTS