CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032096
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 cDNA FLJ56370, highly similar to Homo sapiens FK506 binding protein 8, 38kDa (FKBP8), mRNA 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
278NSYDLAIKAITSSAKubiquitination[1]
300EAQLLQLKVKCLNNLubiquitination[1, 2]
336EHQPDNIKALFRKGKubiquitination[1]
343KALFRKGKVLAQQGEubiquitination[2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 441 AA 
Protein Sequence
MGVGAGRVSQ SGAPSPGGAG RANSCPPSSM ASCAEPSEPS APLPAGVPPL EDFEVLDGVE 60
DAEGEEEEEE EEEEEDDLSE LPPLEDMGQP PAEEAEQPGA LAREFLAAME PEPAPAPAPE 120
EWLDILGNGL LRKKTLVPGP PGSSRPVKGQ VVTVHLQTSL ENGTRVQEEP ELVFTLGDCD 180
VIQALDLSVP LMDVGETAMV TADSKYCYGP QGRSPYIPPH AALCLEVTLK TAVDGPDLEM 240
LTGQERVALA NRKRECGNAH YQRADFVLAA NSYDLAIKAI TSSAKVDMTF EEEAQLLQLK 300
VKCLNNLAAS RLKLDHYRAA LRSCSLVLEH QPDNIKALFR KGKVLAQQGE YSEAIPILRA 360
ALKLEPSNKT IHAELSKLVK KHAAQRSTET ALYRKMLGNP SRLPAKCPGK GAWSIPWKWL 420
FGATAVALGG VALSVVIAAR N 441 
Gene Ontology
 GO:0006457; P:protein folding; IEA:InterPro. 
Interpro
 IPR023114; Elongated_TPR_rpt_dom.
 IPR023566; PPIase_FKBP.
 IPR001179; PPIase_FKBP_dom.
 IPR013026; TPR-contain_dom.
 IPR011990; TPR-like_helical.
 IPR019734; TPR_repeat. 
Pfam
 PF00254; FKBP_C 
SMART
  
PROSITE
 PS50059; FKBP_PPIASE
 PS50005; TPR
 PS50293; TPR_REGION 
PRINTS