CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032724
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 ATP-dependent RNA helicase, putative 
Protein Synonyms/Alias
  
Gene Name
 TGVEG_052310 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Toxoplasma gondii 
NCBI Taxa ID
 5811 
Lysine Modification
Position
Peptide
Type
References
453EAREGSEKKPAGWGEacetylation[1]
Reference
 [1] Protein intrinsic disorder in the acetylome of intracellular and extracellular Toxoplasma gondii.
 Xue B, Jeffers V, Sullivan WJ, Uversky VN.
 Mol Biosyst. 2013 Apr 5;9(4):645-57. [PMID: 23403842
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Helicase; Hydrolase; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1544 AA 
Protein Sequence
MNSSSSSRRR RHSDFSSDDG HHHRAFSRSY YDPSRRSRRD SEERDRNSSS LHYSRHSSSR 60
PPSERDAGRH SSRREREEER GSRSSRSGRQ ERRNDEGSER RTEGKSGKRR DERSQGRSER 120
RSVAPDERHG GYDRGNDTDK SERGSRGRRQ SESDSRSPSR EKRRRQRRKD REAERERYSS 180
SRGRDERDRR RHDRLSGSDS GSDGERETKR RRRSAEKSEA REEKVQRGLE KCKSLENKPR 240
EKTDKGAEEE RKTRLERFKQ LAKETSPNGE KDLKTSSPAK ERSASPSISS KKIERPEQEA 300
AEAATQGPTS QTSKEGSKIS RLERFKALQQ LKPTSGSPPS LLAPQASTSD SRATVFSAEK 360
EKHGASEKPA GTTSFQAPSS KVSLAPSGDK RDTPQPRLRR LGDSAAVQAA KAAASAAATA 420
VAALAAQTLS ASRGGREAGE KNKVEEAREG SEKKPAGWGE SRETSGDAGQ KPSAPLGANI 480
DVIYGGERLR KTVKAGGEAV APGGRDKGAV EDREGREETK GDDGDAETQE TQEAQETEGV 540
EDEQGRQGNG SKKKMSKAKE RKQRQQFLLR TIAMKTQSEN TADDPLDAFM TALESEAKEE 600
LDAAKEEERG RVAQLRCLNT KGKKEAAKPK KEAASTVDAS RSISLEEISR WAEVEHQFIP 660
VKAEREKPSG ERDSSSSLVK EEQTPSDDAS SPSKPASLPS GSSEGASSAP HAQTLETGET 720
TREETRSLEK PEASANLAAV DERGEGMETD PSRLRVKSEP ADAAPSDSAS WAPPARDGPR 780
DTVETAAETH ADAAAEAAAA VAAGGAGEEG AKDEDDAYYR VFMEEMKKKK EEAQRLEEER 840
EKRLKMTRAV IAGEVGRGPR EKKKRRRVEE EEDERVFSDG EEEDSSEEEG EGKDPGAQGD 900
EENLSYFDLL MKVGAKKQLP TVDHEASAYP PIKKNLYIQV KEITCMKDHE VDALRKTHGN 960
IKVRGKQCPR PITTFFQCGL PDKIVKYLTL RGITEPFPIQ MQAIPCLMCG RDVIAVAETG 1020
SGKTLAYGLP LIRHVLSVKQ QDFRDGAIAL VIAPTRELCN QIFKEINRCC KLVDLNAVAC 1080
YGGAGIGSQL GAIKRGVEVI VGTPGRLIDI LTMNGGRLTS LKRVTFIVLD EADRMFDFGF 1140
EPQVTSIIAS SRPDRQTCLF SATFPPHIEA LARRILQKPV EIIVGEKGRT AANVQQYVEV 1200
MEEERKFFRL LQLLGEWQEH GSVIIFVNRQ VEADELFTEL LKYGYQAATL HGGQDQTDRE 1260
FTIQEFQDGV RTLLIATSVA ARGLDCKHCV LVINMTCPNH IEDYVHRIGR TGRAGRIGVA 1320
YTFLTKEDAD KADDLEKALT QSGQAVPQAL SDLSAQYKQE CNLGMHEKKK KGGGGFGGRG 1380
FSFSASEKSR QQRERQQAKK ELGLEKDAED EEFLDADLLA PEDVLGPSGD REPEGRGAAV 1440
DPVTGLPVNF SAATVLSSAT DGNSLQSAVA AAAAKAASLA QRQAASSGPG LASSEGAERA 1500
RVVAELLRSA NGGGDRTEAR HGARSGRKAK TSKEEEEERA MGDS 1544 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
 GO:0003676; F:nucleic acid binding; IEA:InterPro. 
Interpro
 IPR011545; DNA/RNA_helicase_DEAD/DEAH_N.
 IPR014001; Helicase_ATP-bd.
 IPR001650; Helicase_C.
 IPR027417; P-loop_NTPase.
 IPR000629; RNA-helicase_DEAD-box_CS.
 IPR014014; RNA_helicase_DEAD_Q_motif. 
Pfam
 PF00270; DEAD
 PF00271; Helicase_C 
SMART
 SM00487; DEXDc
 SM00490; HELICc 
PROSITE
 PS00039; DEAD_ATP_HELICASE
 PS51192; HELICASE_ATP_BIND_1
 PS51194; HELICASE_CTER
 PS51195; Q_MOTIF 
PRINTS