UniProt Accession

 CYHR1_HUMAN; Q6ZMK1; B3KSX0; D3DWM3; Q9BSF6; Q9BSU6 

Genbank Protein ID

 AB007965; AK094514; AK160381; CH471162; CH471162; CH471162; BC004544; BC005073; BC065484 

Genbank Nucleotide ID

 BAG52882.1; BAD18724.1; EAW82088.1; EAW82089.1; EAW82091.1; AAH04544.2; AAH05073.1; AAH65484.1 

Protein Name

 Cysteine and histidine-rich protein 1 

Protein Synonyms/Alias

  

Gene Name

 CYHR1 

Gene Synonyms/Alias

 KIAA0496 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
292	FQLLLKSKVTAPLEC	ubiquitination	[1, 2]
349	CNKLLAAKNINLRLF	ubiquitination	[1, 2]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 

Functional Description

  

Sequence Annotation

 ZN_FING 68 114 RING-type; degenerate.
 ZN_FING 110 183 TRAF-type.  

Keyword

 Alternative splicing; Complete proteome; Cytoplasm; Metal-binding; Reference proteome; Zinc; Zinc-finger. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 362 AA 

Protein Sequence

Gene Ontology

 GO:0005635; C:nuclear envelope; IEA:Compara.
 GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
 GO:0008270; F:zinc ion binding; IEA:InterPro. 

Interpro

 IPR008974; TRAF-like.
 IPR013083; Znf_RING/FYVE/PHD.
 IPR001293; Znf_TRAF. 

Pfam

  

SMART

  

PROSITE

 PS00518; ZF_RING_1
 PS50089; ZF_RING_2
 PS50145; ZF_TRAF 

PRINTS