CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-012944
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Mitochondrial import receptor subunit TOM34 
Protein Synonyms/Alias
 Translocase of outer membrane 34 kDa subunit 
Gene Name
 Tomm34 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
197VERARVLKEEGNELVacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405
Functional Description
 Plays a role in the import of cytosolically synthesized preproteins into mitochondria. Binds the mature portion of precursor proteins. Interacts with cellular components, and possesses weak ATPase activity. May be a chaperone-like protein that helps to keep newly synthesized precursors in an unfolded import compatible state (By similarity). 
Sequence Annotation
 REPEAT 9 42 TPR 1.
 REPEAT 51 84 TPR 2.
 REPEAT 86 118 TPR 3.
 REPEAT 193 226 TPR 4.
 REPEAT 227 260 TPR 5.
 REPEAT 262 294 TPR 6.
 MOD_RES 186 186 Phosphoserine.  
Keyword
 Chaperone; Complete proteome; Cytoplasm; Membrane; Mitochondrion; Mitochondrion outer membrane; Phosphoprotein; Reference proteome; Repeat; TPR repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 309 AA 
Protein Sequence
MAPKVSDSVE QLRAAGNQNF RNGQYGEASA LYERALRLLQ ARGSADPEEE SVLYSNRAAC 60
YLKDGNCTDC IKDCTSALAL VPFSIKPLLR RASAYEALEK YSLAYVDYKT VLQIDNSVAS 120
ALEGINRITR ALMDSLGPEW RLKLPPIPVV PVSAQKRWSS LPSENHKETA KSKSKETTAT 180
KNRVPSAGDV ERARVLKEEG NELVKKGNHK KAIEKYSESL LFSSLESATY SNRALCHLVL 240
KQYKEAEKDC TEALKLDGKN VKAFYRRAQA YKALKDYKSS LADISSLLQI EPRNGPAHKL 300
RQEVNQNMN 309 
Gene Ontology
 GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
 GO:0006626; P:protein targeting to mitochondrion; IEA:Compara. 
Interpro
 IPR001440; TPR-1.
 IPR013026; TPR-contain_dom.
 IPR011990; TPR-like_helical.
 IPR019734; TPR_repeat. 
Pfam
 PF00515; TPR_1 
SMART
 SM00028; TPR 
PROSITE
 PS50005; TPR
 PS50293; TPR_REGION 
PRINTS