UniProt Accession

 LSM1_YEAST; P47017; D6VW62 

Genbank Protein ID

 Z49399; AY558307; BK006943 

Genbank Nucleotide ID

 CAA89419.1; AAS56633.1; DAA08678.1 

Protein Name

 Sm-like protein LSm1 

Protein Synonyms/Alias

 SPB8 protein 

Gene Name

 LSM1 

Gene Synonyms/Alias

 SPB8; YJL124C; J0714 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
93	IYFSEENKYAEEDRG	ubiquitination	[1]
133	AMERIPFKEAWLTKQ	ubiquitination	[1]
168	GIVYDFHKSDMY***	ubiquitination	[1]

Reference

 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 

Functional Description

 Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation by activating the decapping step. 

Sequence Annotation

  

Keyword

 Complete proteome; Cytoplasm; mRNA processing; Nucleus; Reference proteome; Ribonucleoprotein. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 172 AA 

Protein Sequence

Gene Ontology

 GO:0000932; C:cytoplasmic mRNA processing body; IDA:SGD.
 GO:0005845; C:mRNA cap binding complex; IPI:SGD.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0000339; F:RNA cap binding; IGI:SGD.
 GO:0000290; P:deadenylation-dependent decapping of nuclear-transcribed mRNA; IGI:SGD.
 GO:0006397; P:mRNA processing; IEA:UniProtKB-KW. 

Interpro

 IPR010920; LSM_dom.
 IPR001163; Ribonucl_LSM.
 IPR006649; Ribonucl_LSM_euk/arc. 

Pfam

 PF01423; LSM 

SMART

 SM00651; Sm 

PROSITE

  

PRINTS