CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015835
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 CaiB/baiF CoA-transferase family protein C7orf10 homolog 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
37QSDCDSMKPLEGVRIacetylation[1]
306PELIDDCKYRTNHLRacetylation[2, 3]
322QNRKELVKILSARFAacetylation[2, 3]
392AVRYSKFKMSEAKPPacetylation[1, 2, 3]
411QHTRHILKEVLRYDEacetylation[3]
423YDEGAIEKLLCSGVIacetylation[1, 2, 3, 4]
Reference
 [1] Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.
 Rardin MJ, Newman JC, Held JM, Cusack MP, Sorensen DJ, Li B, Schilling B, Mooney SD, Kahn CR, Verdin E, Gibson BW.
 Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6. [PMID: 23576753]
 [2] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123]
 [3] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654]
 [4] Quantitative assessment of the impact of the gut microbiota on lysine epsilon-acetylation of host proteins using gnotobiotic mice.
 Simon GM, Cheng J, Gordon JI.
 Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11133-8. [PMID: 22733758
Functional Description
  
Sequence Annotation
 ACT_SITE 203 203 Nucleophile (By similarity).  
Keyword
 Complete proteome; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 436 AA 
Protein Sequence
MLWMLARAVA FRRPGRGLAG GRGLWTGRPQ SDCDSMKPLE GVRILDLTRV LAGPFATMNL 60
GDLGAEVIKV ERPGAGDDTR SWGPPFVNTE STYFLSVNRN KKSIAVNIKD PRGVRIVKEL 120
AAICDVFVEN YVPGKLSEMG LGYEDIDKIA PHIIYCSITG YGQTGPMSHR AGYDAIASAM 180
SGLMHITGPE DGDPVRPGVA MTDLATGLFA YGAIMAGLLQ RYRTGKGLFI DCNLLSSQVA 240
CLTQVAANYL IGQKEAKRWG TAHGSIVPYQ AFKTKDGYLV IGAGNNQQFA VVCKILNLPE 300
LIDDCKYRTN HLRVQNRKEL VKILSARFAE EVTAKWLCLF EGSGIPYGPI NSLKDVFSEA 360
QVLHNGLVME MNHPTVGKIS VPGPAVRYSK FKMSEAKPPP LLGQHTRHIL KEVLRYDEGA 420
IEKLLCSGVI EQHETK 436 
Gene Ontology
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0016740; F:transferase activity; IEA:UniProtKB-KW. 
Interpro
 IPR003673; CoA-Trfase_fam_III.
 IPR023606; CoA-Trfase_III_dom. 
Pfam
 PF02515; CoA_transf_3 
SMART
  
PROSITE
  
PRINTS