CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-019676
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 DNA-directed RNA polymerase subunit A' 
Protein Synonyms/Alias
  
Gene Name
 rpoA1 
Gene Synonyms/Alias
 SSO0225 
Created Date
 July 27, 2013 
Organism
 Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322  
NCBI Taxa ID
 273057 
Lysine Modification
Position
Peptide
Type
References
395LRYVKDRKELASTLAmethylation[1]
659SLGDDVKKEIYNEIDmethylation[1]
Reference
 [1] Extensive lysine methylation in hyperthermophilic crenarchaea: potential implications for protein stability and recombinant enzymes.
 Botting CH, Talbot P, Paytubi S, White MF.
 Archaea. 2010 Aug 5;2010. [PMID: 20811616
Functional Description
 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. 
Sequence Annotation
 ZN_FING 58 101 C4-type (Potential).  
Keyword
 3D-structure; Complete proteome; DNA-directed RNA polymerase; Metal-binding; Nucleotidyltransferase; Reference proteome; Transcription; Transferase; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 880 AA 
Protein Sequence
MSEKNIKGIK FGILSPDEIR KMSVTAIITP DVYDEDGTPI EGSVMDPRLG VIEPGQKCPT 60
CGNTLGNCPG HFGHIELVRP VIHVGLVKHI YEFLKATCRR CGRVKISEDE IEKYSRIYNA 120
IKKRWPSAAR RLTEYVKKTA MKAQVCPHCN EKQYKIKLEK PYNFYEERKE GVAKLTPSDI 180
RERLEKIPDS DVEILGYDPT TSRPEWMILT VLPVPPITIR PSIMIESGIR AEDDLTHKLV 240
DIVRINERLK ESIDAGAPQL IIEDLWDLLQ YHVATYFDNE IPGLPPSKHR SGRPLRTLAQ 300
RLKGKEGRFR GNLSGKRVDF SSRTVISPDP NISIDEVGVP EIIAKTLTVP ERITPWNIEK 360
LRQFVINGPD KWPGANYVIR PDGRRIDLRY VKDRKELAST LAPGYIIERH LIDGDIVLFN 420
RQPSLHRISM MAHRVRVLKG LTFRLNLLVC PPYNADFDGD EMNLHVPQSE EAIAEAKEIM 480
LVHKNIITPR YGGPIIGAAQ DYISGAYLLT VKTTLLTKEE AQQILGVADV KIDLGEPAIL 540
APREYYTGKQ VISAFLPKDF NFHGQANVSS GPRLCKNEDC PHDSYVVIKN GILLEGVFDK 600
KAIGNQQPES ILHWLIKEYS DEYGKWLMDN LFRVFIRFVE LQGFTMRLED VSLGDDVKKE 660
IYNEIDRAKV EVDNLIQKYK NGELEPIPGR TLEESLENYI LDTLDKLRST AGDIASKYLD 720
PFNFAYVMAR TGARGSVLNI TQMAAMLGQQ SVRGERIKRG YMTRTLPHFK PYDISPEARG 780
FIYSSFRTGL KPTELFFHAA GGREGLVDTA VRTSQSGYMQ RRLINALSDL RAEYDGTVRS 840
LYGEVVQVAY GDDGVFPMYS AHGKTVDVNR IFERVVGWKA 880 
Gene Ontology
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006351; P:transcription, DNA-dependent; IEA:InterPro. 
Interpro
 IPR009010; Asp_de-COase-like_dom.
 IPR000722; RNA_pol_asu.
 IPR006592; RNA_pol_N.
 IPR007080; RNA_pol_Rpb1_1.
 IPR007066; RNA_pol_Rpb1_3.
 IPR007083; RNA_pol_Rpb1_4.
 IPR007081; RNA_pol_Rpb1_5.
 IPR012758; RNAP_A1. 
Pfam
 PF04997; RNA_pol_Rpb1_1
 PF00623; RNA_pol_Rpb1_2
 PF04983; RNA_pol_Rpb1_3
 PF05000; RNA_pol_Rpb1_4
 PF04998; RNA_pol_Rpb1_5 
SMART
 SM00663; RPOLA_N 
PROSITE
  
PRINTS