UniProt Accession

 GNA1_YEAST; P43577; D6VTL3 

Genbank Protein ID

 AB017626; D50617; Z46255; AY558564; BK006940 

Genbank Nucleotide ID

 BAA36495.1; BAA09221.1; CAA86352.1; AAS56890.1; DAA12423.1 

Protein Name

 Glucosamine 6-phosphate N-acetyltransferase 

Protein Synonyms/Alias

 Phosphoglucosamine acetylase; Phosphoglucosamine transacetylase 

Gene Name

 GNA1 

Gene Synonyms/Alias

 PAT1; YFL017C 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
70	NPMVIVDKRTETVAA	ubiquitination	[1]
138	IILDCDEKNVKFYEK	acetylation	[2]

Reference

 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [2] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 

Functional Description

  

Sequence Annotation

 DOMAIN 28 159 N-acetyltransferase.
 REGION 86 89 Substrate binding.
 REGION 98 100 Substrate binding.
 REGION 100 102 Acetyl-CoA binding.
 REGION 108 113 Acetyl-CoA binding.
 REGION 129 130 Substrate binding.
 REGION 143 145 Acetyl-CoA binding.
 BINDING 28 28 Substrate.
 BINDING 134 134 Substrate; via carbonyl oxygen.
 BINDING 158 158 Substrate.  

Keyword

 3D-structure; Acyltransferase; Complete proteome; Reference proteome; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 159 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:SGD.
 GO:0005634; C:nucleus; IDA:SGD.
 GO:0004343; F:glucosamine 6-phosphate N-acetyltransferase activity; IDA:SGD.
 GO:0006048; P:UDP-N-acetylglucosamine biosynthetic process; IDA:SGD. 

Interpro

 IPR016181; Acyl_CoA_acyltransferase.
 IPR000182; GNAT_dom. 

Pfam

 PF00583; Acetyltransf_1 

SMART

  

PROSITE

 PS51186; GNAT 

PRINTS