UniProt Accession

 RPE_ECOLI; P0AG07; P32661; Q2M751 

Genbank Protein ID

 Z19601; U18997; U00096; AP009048 

Genbank Nucleotide ID

 CAA79663.1; AAA58183.1; AAC76411.1; BAE77905.1 

Protein Name

 Ribulose-phosphate 3-epimerase 

Protein Synonyms/Alias

 Pentose-5-phosphate 3-epimerase; PPE; R5P3E 

Gene Name

 rpe 

Gene Synonyms/Alias

 dod; yhfD; b3386; JW3349 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
24	RLGEDTAKALAAGAD	acetylation	[1]
72	IDVHLMVKPVDRIVP	acetylation	[1]
210	FDQPDYKKVIDEMRS	acetylation	[1]
221	EMRSELAKVSHE***	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate. 

Sequence Annotation

 REGION 144 147 Substrate binding (By similarity).
 REGION 199 200 Substrate binding (By similarity).
 ACT_SITE 36 36 Proton acceptor (By similarity).
 ACT_SITE 177 177 Proton donor (By similarity).
 METAL 34 34 Divalent metal cation (By similarity).
 METAL 36 36 Divalent metal cation (By similarity).
 METAL 68 68 Divalent metal cation (By similarity).
 METAL 177 177 Divalent metal cation (By similarity).
 BINDING 9 9 Substrate (By similarity).
 BINDING 68 68 Substrate (By similarity).
 BINDING 179 179 Substrate; via amide nitrogen (By  

Keyword

 Carbohydrate metabolism; Cobalt; Complete proteome; Iron; Isomerase; Manganese; Metal-binding; Reference proteome; Zinc. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 225 AA 

Protein Sequence

Gene Ontology

 GO:0008198; F:ferrous iron binding; IDA:EcoCyc.
 GO:0004750; F:ribulose-phosphate 3-epimerase activity; IDA:EcoCyc.
 GO:0019323; P:pentose catabolic process; IMP:EcoCyc.
 GO:0009052; P:pentose-phosphate shunt, non-oxidative branch; IGI:EcoCyc. 

Interpro

 IPR013785; Aldolase_TIM.
 IPR026019; Ribul_P_3_epim.
 IPR000056; Ribul_P_3_epim-like.
 IPR011060; RibuloseP-bd_barrel. 

Pfam

 PF00834; Ribul_P_3_epim 

SMART

  

PROSITE

 PS01085; RIBUL_P_3_EPIMER_1
 PS01086; RIBUL_P_3_EPIMER_2 

PRINTS