| Tag | Content |
|---|
| CPLM ID | CPLM-011998 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Zinc finger protein 154 |
Protein Synonyms/Alias | |
Gene Name | ZNF154 |
Gene Synonyms/Alias | KIAA2003 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 187 | WRLHTGEKPYECREC | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | May be involved in transcriptional regulation. |
Sequence Annotation | DOMAIN 14 88 KRAB.
ZN_FING 89 111 C2H2-type 1; degenerate.
ZN_FING 133 155 C2H2-type 2; degenerate.
ZN_FING 161 183 C2H2-type 3.
ZN_FING 189 211 C2H2-type 4.
ZN_FING 217 239 C2H2-type 5.
ZN_FING 245 267 C2H2-type 6.
ZN_FING 273 295 C2H2-type 7.
ZN_FING 301 323 C2H2-type 8.
ZN_FING 329 351 C2H2-type 9.
ZN_FING 357 379 C2H2-type 10.
ZN_FING 385 407 C2H2-type 11.
ZN_FING 413 435 C2H2-type 12. |
Keyword | Complete proteome; DNA-binding; Metal-binding; Nucleus; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 437 AA |
Protein Sequence | MAAATLRTPT QGTVTFEDVA VHFSWEEWGL LDEAQRCLYR DVMLENLALL TSLDVHHQKQ 60
HLGEKHFRSN VGRALFVKTC TFHVSGEPST CREVGKDFLA KLGFLHQQAA HTGEQSNSKS 120
DGGAISHRGK THYNCGEHTK AFSGKHTLVQ QQRTLTTERC YICSECGKSF SKSYSLNDHW 180
RLHTGEKPYE CRECGKSFRQ SSSLIQHRRV HTAVRPHECD ECGKLFSNKS NLIKHRRVHT 240
GERPYECSEC GKSFSQRSAL LQHRGVHTGE RPYECSECGK FFTYHSSLIK HQKVHSGSRP 300
YECSECGKSF SQNSSLIEHH RVHTGERPYK CSECGKSFSQ RSALLQHRGV HTGERPYECS 360
ECGKFFPYSS SLRKHQRVHT GSRPYECSEC GKSFTQNSGL IKHRRVHTGE KPYECTECGK 420
SFSHNSSLIK HQRIHSR 437 |
Gene Ontology | GO:0005634; C:nucleus; NAS:UniProtKB. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |