| Tag | Content |
|---|
| CPLM ID | CPLM-008696 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Protein SOK2 |
Protein Synonyms/Alias | |
Gene Name | SOK2 |
Gene Synonyms/Alias | YMR016C; YM9711.03C |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 696 | SESASHSKWSKEADS | acetylation | [1] | | 733 | LTSTDTDKIKTSTSD | acetylation | [1] |
|
Reference | [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [ PMID: 22865919] |
Functional Description | Plays a general regulatory role in the cyclic AMP- dependent protein kinase-stimulated (PKA) signal transduction pathway by regulating the expression of genes important in growth and development. May inhibit the switch from unicellular to filamentous growth. |
Sequence Annotation | DOMAIN 414 520 HTH APSES-type.
DNA_BIND 448 469 H-T-H motif (By similarity).
MOD_RES 719 719 Phosphoserine; by ATM or ATR.
MOD_RES 771 771 Phosphoserine. |
Keyword | Complete proteome; DNA-binding; Nucleus; Phosphoprotein; Reference proteome; Transcription; Transcription regulation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 785 AA |
Protein Sequence | MPIGNPINTN DIKSNRMRQE SNMSAVSNSE STIGQSTQQQ QQQQQYLGQS VQPLMPVSYQ 60
YVVPEQWPYP QYYQQPQSQS QQQLQSQPQM YQVQESFQSS GSDSNASNPP STSVGVPSNA 120
TATALPNGSA ITTKKSNNST NISNNVPYYY YFPQMQAQQS MAYSYPQAYY YYPANGDGTT 180
NGATPSVTSN QVQNPNLEKT YSTFEQQQQH QQQQQLQAQT YPAQPPKIGN AFSKFSKSGP 240
PSDSSSGSMS PNSNRTSRNS NSISSLAQQP PMSNYPQPST YQYPGFHKTS SIPNSHSPIP 300
PRSLTTPTQG PTSQNGPLSY NLPQVGLLPP QQQQQVSPLY DGNSITPPVK PSTDQETYLT 360
ANRHGVSDQQ YDSMAKTMNS FQTTTIRHPM PLIATTNATG SNTSGTSASI IRPRVTTTMW 420
EDEKTLCYQV EANGISVVRR ADNDMVNGTK LLNVTKMTRG RRDGILKAEK IRHVVKIGSM 480
HLKGVWIPFE RALAIAQREK IADYLYPLFI RDIQSVLKQN NPSNDSSSSS SSTGIKSISP 540
RTYYQPINNY QNPNGPSNIS AAQLTYSSMN LNNKIIPNNS IPAVSTIAAG EKPLKKCTMP 600
NSNQLEGHTI TNLQTLSATM PMKQQLMGNI ASPLSYPRNA TMNSASTLGI TPADSKPLTP 660
SPTTTNTNQS SESNVGSIHT GITLPRVESE SASHSKWSKE ADSGNTVPDN QTLKEPRSSQ 720
LPISALTSTD TDKIKTSTSD EATQPNEPSE AEPVKESESS KSQVDGAGDV SNEEIAADDT 780
KKQEK 785 |
Gene Ontology | GO:0005829; C:cytosol; IDA:SGD. GO:0005634; C:nucleus; IDA:SGD. GO:0043565; F:sequence-specific DNA binding; IDA:SGD. GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:SGD. GO:0007124; P:pseudohyphal growth; IMP:SGD. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |