CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037564
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein phosphatase Slingshot homolog 3 
Protein Synonyms/Alias
  
Gene Name
 SSH3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
33AIRAELWKVLDVSDLubiquitination[1]
46DLESVTSKEIRQALEubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Hydrolase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 207 AA 
Protein Sequence
MADLESLRPP SAEPGGSSEQ EQMEQAIRAE LWKVLDVSDL ESVTSKEIRQ ALELRLGLPL 60
QQYRDFIDNQ MLLLVAQRDR ASRIFPHLYL GSEWNAANLE ELQRNRAQGT HVLVHCKMGV 120
SRSAATVLAY AMKQYECSLE QALRHVQELR PIARPNPGFL RQLQIYQGIL TASRQSHVWE 180
QKVGGVSPEE HPAPEVSTPF PPLPPEP 207 
Gene Ontology
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
 GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
 GO:0035335; P:peptidyl-tyrosine dephosphorylation; IEA:GOC. 
Interpro
 IPR014876; DEK_C.
 IPR000340; Dual-sp_phosphatase_cat-dom.
 IPR020422; Dual-sp_phosphatase_subgr_cat.
 IPR024950; DUSP.
 IPR009057; Homeodomain-like.
 IPR000387; Tyr/Dual-sp_Pase.
 IPR016130; Tyr_Pase_AS. 
Pfam
 PF08766; DEK_C
 PF00782; DSPc 
SMART
  
PROSITE
 PS00383; TYR_PHOSPHATASE_1
 PS50056; TYR_PHOSPHATASE_2
 PS50054; TYR_PHOSPHATASE_DUAL 
PRINTS