CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027558
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Phosphoenolpyruvate carboxykinase 
Protein Synonyms/Alias
 Phosphoenolpyruvate carboxykinase, putative 
Gene Name
 pck 
Gene Synonyms/Alias
 TGGT1_033560; TGME49_089650; TGVEG_083410 
Created Date
 July 27, 2013 
Organism
 Toxoplasma gondii 
NCBI Taxa ID
 5811 
Lysine Modification
Position
Peptide
Type
References
591EGRRIPLKYTRLMVDacetylation[1, 2]
Reference
 [1] Lysine acetylation is widespread on proteins of diverse function and localization in the protozoan parasite Toxoplasma gondii.
 Jeffers V, Sullivan WJ Jr.
 Eukaryot Cell. 2012 Jun;11(6):735-42. [PMID: 22544907]
 [2] Protein intrinsic disorder in the acetylome of intracellular and extracellular Toxoplasma gondii.
 Xue B, Jeffers V, Sullivan WJ, Uversky VN.
 Mol Biosyst. 2013 Apr 5;9(4):645-57. [PMID: 23403842] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Kinase; Lyase; Pyruvate; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 677 AA 
Protein Sequence
MNYTMHLSRN VLREVYRFLP GRGFLPAQGS TASRVRHSLA DKEFPCCSRS ETCGLHIAEV 60
RHTFFRQLRG SSGVNRKSSD AQRQFVVQFS RSVRKMNRTQ SSGSLKDSIS FLEMLKKQID 120
ANLQHHKPGD CPLTKKDILD LGQLQKEIDF QENVQAVGIT CAQLFHNTAP SVLYEQALKK 180
EAGSLIASSG ALCVSSGLKT GRSPADKRIV EEPSSRDDVW WGKVNIPFCE KSYLVNRERA 240
VDYLNLQDQL YIVDAFAGWD PEYRIKIRVI TTRAYHALFM QNMLVMPTAE ELENFRPDFT 300
IYNAGCFPAN RFTNGVTSQT SVAMNLGAGE MVILGTQYAG EMKKGILTLM MYLMPKRGQL 360
PLHSSCNVGP KGDVTLFFGL SGTGKTTLSA DPSRQLIGDD EHVWTDKGVF NIEGGCYAKC 420
KDLSKEQEPE IWNAIRFGSV LENVIIDGTT RVVDFRDVSI TENTRCAYPL SFIPNALLPA 480
KVDTHPSNII LLTCDAFGVL PPLSKLTPDQ VMYHFISGYT SKMAGTEIGI LEPTATFSAC 540
YGAPFLAMHP MVYAEMLAKK LKEHNAHAWL LNTGWICGGY GMNEGRRIPL KYTRLMVDAI 600
HNGAALQTEY QTMPVFNLAV PTAINGVPSD LLLPQTCWAD QNKLDKQMRK LASLFVENFS 660
NYTDRATPNV VAAGPVF 677 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
 GO:0004612; F:phosphoenolpyruvate carboxykinase (ATP) activity; IEA:EC.
 GO:0006094; P:gluconeogenesis; IEA:InterPro. 
Interpro
 IPR001272; PEP_carboxykinase_ATP.
 IPR013035; PEP_carboxykinase_C.
 IPR008210; PEP_carboxykinase_N.
 IPR015994; PEPCK_ATP_CS. 
Pfam
 PF01293; PEPCK_ATP 
SMART
  
PROSITE
 PS00532; PEPCK_ATP 
PRINTS