UniProt Accession

 GPX2_YEAST; P38143; D6VQP0 

Genbank Protein ID

 Z36113; AY557641; BK006936 

Genbank Nucleotide ID

 CAA85207.1; AAS55967.1; DAA07360.1 

Protein Name

 Glutathione peroxidase 2 

Protein Synonyms/Alias

  

Gene Name

 GPX2 

Gene Synonyms/Alias

 YBR244W; YBR1632 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
125	LLGFKGIKWNFEKFL	acetylation	[1]

Reference

 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 

Functional Description

 May constitute a glutathione peroxidase-like protective system against oxidative stresses (By similarity). 

Sequence Annotation

 ACT_SITE 37 37 By similarity.  

Keyword

 Complete proteome; Oxidoreductase; Peroxidase; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 162 AA 

Protein Sequence

Gene Ontology

 GO:0031314; C:extrinsic to mitochondrial inner membrane; IDA:SGD.
 GO:0031315; C:extrinsic to mitochondrial outer membrane; IDA:SGD.
 GO:0005634; C:nucleus; IDA:SGD.
 GO:0004602; F:glutathione peroxidase activity; IDA:SGD.
 GO:0047066; F:phospholipid-hydroperoxide glutathione peroxidase activity; IMP:SGD.
 GO:0034599; P:cellular response to oxidative stress; IMP:SGD. 

Interpro

 IPR000889; Glutathione_peroxidase.
 IPR012336; Thioredoxin-like_fold. 

Pfam

 PF00255; GSHPx 

SMART

  

PROSITE

 PS00460; GLUTATHIONE_PEROXID_1
 PS00763; GLUTATHIONE_PEROXID_2
 PS51355; GLUTATHIONE_PEROXID_3 

PRINTS

 PR01011; GLUTPROXDASE.