UniProt Accession

 BFR_ECOLI; P0ABD3; O68931; P11056; Q2M701 

Genbank Protein ID

 M27176; AF058450; U18997; U00096; AP009048; L28106 

Genbank Nucleotide ID

 AAC13987.1; AAC14288.1; AAA58133.1; AAC76361.1; BAE77955.1; AAC36929.1 

Protein Name

 Bacterioferritin 

Protein Synonyms/Alias

 BFR; Cytochrome b-1; Cytochrome b-557 

Gene Name

 bfr 

Gene Synonyms/Alias

 b3336; JW3298 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
2	******MKGDTKVIN	acetylation	[1]
6	**MKGDTKVINYLNK	acetylation	[1]
33	FLHARMFKNWGLKRL	acetylation	[1]
38	MFKNWGLKRLNDVEY	acetylation	[1]
53	HESIDEMKHADRYIE	acetylation	[1]
99	ALELDGAKNLREAIG	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex. The mineralized iron core can contain as many as 2700 iron atoms/24-meric molecule. 

Sequence Annotation

 DOMAIN 1 145 Ferritin-like diiron.
 METAL 18 18 Iron 1.
 METAL 46 46 Iron 3.
 METAL 50 50 Iron 3.
 METAL 51 51 Iron 1.
 METAL 51 51 Iron 2.
 METAL 52 52 Iron (heme axial ligand); shared with
 METAL 54 54 Iron 1.
 METAL 94 94 Iron 2.
 METAL 127 127 Iron 1.
 METAL 127 127 Iron 2.
 METAL 130 130 Iron 2.  

Keyword

 3D-structure; Complete proteome; Direct protein sequencing; Heme; Iron; Iron storage; Metal-binding; Oxidoreductase; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 158 AA 

Protein Sequence

Gene Ontology

 GO:0005829; C:cytosol; IDA:UniProtKB.
 GO:0016020; C:membrane; IDA:UniProtKB.
 GO:0008199; F:ferric iron binding; IEA:InterPro.
 GO:0004322; F:ferroxidase activity; IEA:EC.
 GO:0005506; F:iron ion binding; IDA:EcoCyc.
 GO:0016491; F:oxidoreductase activity; NAS:EcoliWiki.
 GO:0006880; P:intracellular sequestering of iron ion; IDA:EcoCyc.
 GO:0006826; P:iron ion transport; IEA:InterPro. 

Interpro

 IPR002024; Bacterioferritin.
 IPR009040; Ferritin-like_diiron.
 IPR009078; Ferritin-like_SF.
 IPR012347; Ferritin-rel.
 IPR008331; Ferritin_DPS_dom. 

Pfam

 PF00210; Ferritin 

SMART

  

PROSITE

 PS00549; BACTERIOFERRITIN
 PS50905; FERRITIN_LIKE 

PRINTS

 PR00601; BACFERRITIN.