CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037332
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Golgi SNAP receptor complex member 1 
Protein Synonyms/Alias
  
Gene Name
 GOSR1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
186ISIAMATKENMTSQRubiquitination[1, 2, 3]
202MLKSIHSKMNTLANRubiquitination[1, 4]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [4] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 
Functional Description
 Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide- sensitive factor) attachment protein receptor (By similarity). 
Sequence Annotation
  
Keyword
 Complete proteome; ER-Golgi transport; Golgi apparatus; Membrane; Protein transport; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 248 AA 
Protein Sequence
MAAGTSSYWE DLRKQARQLE NELDLKLVSF SKLCTSYSHS STRDGRRDSS DTTPLLNGSS 60
QDRMFETMAI EIEQLLARLT GVNDKMAEYT NSAGVPSLNA ALMHTLQRHR DILQDYTHEF 120
HKTKANFMAI RERENLMGSV RKDIESYKSG SGVNNRRTEL FLKEHDHLRN SDRLIEETIS 180
IAMATKENMT SQRGMLKSIH SKMNTLANRF PAVNSLIQRI NLRKRRDSLI LGGVIGICTI 240
LLLLYAFH 248 
Gene Ontology
 GO:0005801; C:cis-Golgi network; IEA:InterPro.
 GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; IEA:InterPro.
 GO:0006888; P:ER to Golgi vesicle-mediated transport; IEA:InterPro.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW. 
Interpro
 IPR023601; Golgi_SNAP_su1. 
Pfam
  
SMART
  
PROSITE
  
PRINTS