UniProt Accession

 Q9BJF5_TOXGO; Q9BJF5; B9Q301; B9QPZ6 

Genbank Protein ID

 AF333958; EQ967506; EQ970706 

Genbank Nucleotide ID

 AAG53993.1; EEE19357.1; EEE27562.1 

Protein Name

 Calmodulin-domain protein kinase 1 

Protein Synonyms/Alias

 Calmodulin-domain protein kinase, putative 

Gene Name

 CDPK1 

Gene Synonyms/Alias

 TGGT1_059880; TGVEG_042030 

Created Date

 July 27, 2013 

Organism

 Toxoplasma gondii 

NCBI Taxa ID

 5811 

Lysine Modification

Position	Peptide	Type	References
266	LKKVEKGKYTFELPQ	acetylation	[1]

Reference

 [1] Lysine acetylation is widespread on proteins of diverse function and localization in the protozoan parasite Toxoplasma gondii.
 Jeffers V, Sullivan WJ Jr.
 Eukaryot Cell. 2012 Jun;11(6):735-42. [PMID: 22544907] 

Functional Description

  

Sequence Annotation

 REGION 209 210 Sulfate 3 binding.
 METAL 368 368 Calcium 1.
 METAL 370 370 Calcium 1.
 METAL 372 372 Calcium 1.
 METAL 374 374 Calcium 1; via carbonyl oxygen.
 METAL 379 379 Calcium 1.
 METAL 415 415 Calcium 2.
 METAL 417 417 Calcium 2.
 METAL 419 419 Calcium 2.
 METAL 421 421 Calcium 2; via carbonyl oxygen.
 METAL 423 423 Calcium 2.
 METAL 426 426 Calcium 2.
 METAL 451 451 Calcium 3.
 METAL 453 453 Calcium 3.
 METAL 455 455 Calcium 3.
 METAL 457 457 Calcium 3; via carbonyl oxygen.
 METAL 462 462 Calcium 3.
 METAL 485 485 Calcium 4.
 METAL 487 487 Calcium 4.
 METAL 489 489 Calcium 4.
 METAL 491 491 Calcium 4; via carbonyl oxygen.
 METAL 496 496 Calcium 4.
 BINDING 132 132 Sulfate 2.
 BINDING 173 173 Sulfate 3.
 BINDING 176 176 Sulfate 4.
 BINDING 185 185 Sulfate 2; via amide nitrogen.
 BINDING 338 338 Sulfate 1.
 BINDING 473 473 Sulfate 5.  

Keyword

 3D-structure; ATP-binding; Calcium; Complete proteome; Kinase; Metal-binding; Nucleotide-binding; Reference proteome; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 507 AA 

Protein Sequence

Gene Ontology

 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC. 

Interpro

 IPR011992; EF-hand-like_dom.
 IPR018247; EF_Hand_1_Ca_BS.
 IPR002048; EF_hand_dom.
 IPR011009; Kinase-like_dom.
 IPR000719; Prot_kinase_cat_dom.
 IPR017441; Protein_kinase_ATP_BS.
 IPR002290; Ser/Thr_dual-sp_kinase_dom.
 IPR008271; Ser/Thr_kinase_AS. 

Pfam

 PF13499; EF_hand_5
 PF00069; Pkinase 

SMART

 SM00054; EFh
 SM00220; S_TKc 

PROSITE

 PS00018; EF_HAND_1
 PS50222; EF_HAND_2
 PS00107; PROTEIN_KINASE_ATP
 PS50011; PROTEIN_KINASE_DOM
 PS00108; PROTEIN_KINASE_ST 

PRINTS