CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-006957
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Phosphoacetylglucosamine mutase 
Protein Synonyms/Alias
 PAGM; Acetylglucosamine phosphomutase; N-acetylglucosamine-phosphate mutase 
Gene Name
 PCM1 
Gene Synonyms/Alias
 AGM1; YEL058W 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
116EFRVELAKLIEHEKIacetylation[1]
276ECGADYVKTNQRLPKubiquitination[2]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919]
 [2] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
 Interconverts GlcNAc-6-P and GlcNAc-1-P. 
Sequence Annotation
 ACT_SITE 67 67 Phosphoserine intermediate.
 METAL 67 67 Magnesium; via phosphate group (By
 METAL 298 298 Magnesium (By similarity).
 METAL 300 300 Magnesium (By similarity).
 METAL 302 302 Magnesium (By similarity).
 MOD_RES 67 67 Phosphoserine.  
Keyword
 Complete proteome; Isomerase; Magnesium; Metal-binding; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 557 AA 
Protein Sequence
MKVDYEQLCK LYDDTCRTKN VQFSYGTAGF RTLAKNLDTV MFSTGILAVL RSLKLQGQYV 60
GVMITASHNP YQDNGVKIVE PDGSMLLATW EPYAMQLANA ASFATNFEEF RVELAKLIEH 120
EKIDLNTTVV PHIVVGRDSR ESSPYLLRCL TSSMASVFHA QVLDLGCVTT PQLHYITDLS 180
NRRKLEGDTA PVATEQDYYS FFIGAFNELF ATYQLEKRLS VPKLFIDTAN GIGGPQLKKL 240
LASEDWDVPA EQVEVINDRS DVPELLNFEC GADYVKTNQR LPKGLSPSSF DSLYCSFDGD 300
ADRVVFYYVD SGSKFHLLDG DKISTLFAKF LSKQLELAHL EHSLKIGVVQ TAYANGSSTA 360
YIKNTLHCPV SCTKTGVKHL HHEAATQYDI GIYFEANGHG TIIFSEKFHR TIKSELSKSK 420
LNGDTLALRT LKCFSELINQ TVGDAISDML AVLATLAILK MSPMDWDEEY TDLPNKLVKC 480
IVPDRSIFQT TDQERKLLNP VGLQDKIDLV VAKYPMGRSF VRASGTEDAV RVYAECKDSS 540
KLGQFCDEVV EHVKASA 557 
Gene Ontology
 GO:0005829; C:cytosol; IBA:RefGenome.
 GO:0005634; C:nucleus; IDA:SGD.
 GO:0000287; F:magnesium ion binding; IEA:InterPro.
 GO:0004610; F:phosphoacetylglucosamine mutase activity; IMP:SGD.
 GO:0004614; F:phosphoglucomutase activity; IBA:RefGenome.
 GO:0034221; P:fungal-type cell wall chitin biosynthetic process; IMP:SGD.
 GO:0019255; P:glucose 1-phosphate metabolic process; IBA:RefGenome.
 GO:0006048; P:UDP-N-acetylglucosamine biosynthetic process; IBA:RefGenome. 
Interpro
 IPR005844; A-D-PHexomutase_a/b/a-I.
 IPR016055; A-D-PHexomutase_a/b/a-I/II/III.
 IPR005845; A-D-PHexomutase_a/b/a-II.
 IPR005843; A-D-PHexomutase_C.
 IPR016066; A-D-PHexomutase_CS.
 IPR016657; PAGM. 
Pfam
 PF02878; PGM_PMM_I
 PF02879; PGM_PMM_II
 PF00408; PGM_PMM_IV 
SMART
  
PROSITE
 PS00710; PGM_PMM 
PRINTS