CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037544
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Ankyrin repeat domain-containing protein 42 
Protein Synonyms/Alias
  
Gene Name
 ANKRD42 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
40AVRAGDVKQLSEIVVubiquitination[1, 2]
157VDPSVTDKREWRPVHubiquitination[1]
281KGDLGMLKKLVEDGVubiquitination[2]
282GDLGMLKKLVEDGVIubiquitination[2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 ANK repeat; Complete proteome; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 527 AA 
Protein Sequence
MPGVANSGPS TSSRETANPC SRKKVHFGSI HDAVRAGDVK QLSEIVVRGA SINELDVLHK 60
FTPLHWAAHS GSLECLHWLL WHGADITHVT TRGWTASHIA AIRGQDACVQ ALIMNGANLT 120
AQDDRGCTPL HLAATHGHSF TLQIMLRSGV DPSVTDKREW RPVHYAAFHG RLGCLQLLVK 180
WGCSIEDVDY NGNLPVHLAA MEGHLHCFKF LVSRMSSATQ VLKAFNDNGE NVLDLAQRFF 240
KQNILQFIQG AEYEGKDLED QETLAFPGHV AAFKGDLGML KKLVEDGVIN INERADNGST 300
PMHKAAGQGH IECLQWLIKM GADSNITNKA GERPSDVAKR FAHLAAVKLL EELQKYDIDD 360
ENEIDENDVK YFIRHGVEGS TDAKDDLCLS DLDKTDARMR AYKKIVELRH LLEIAESNYK 420
HLGGITEEDL KQKKEQLESE KTIKELQGQL EYERLRREKL ECQLDEYRAE VDQLRETLEK 480
IQVPNFVAMV GVLFNTFIFL KKYIQEWPRV QALGWGSLDL NPGYSLF 527 
Gene Ontology
  
Interpro
 IPR002110; Ankyrin_rpt.
 IPR020683; Ankyrin_rpt-contain_dom.
 IPR018247; EF_Hand_1_Ca_BS. 
Pfam
 PF12796; Ank_2 
SMART
 SM00248; ANK 
PROSITE
 PS50297; ANK_REP_REGION
 PS50088; ANK_REPEAT
 PS00018; EF_HAND_1 
PRINTS