CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011259
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Neurogranin 
Protein Synonyms/Alias
 Ng; Protein kinase C substrate 7.5 kDa protein; RC3; NEUG(55-78) 
Gene Name
 Nrgn 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
54KSGECGRKGPGPGGPubiquitination[1]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113
Functional Description
 Regulates the affinity of calmodulin for calcium. Involved in synaptic plasticity and spatial learning (By similarity). 
Sequence Annotation
 DOMAIN 26 47 IQ.
 DOMAIN 48 78 Collagen-like.
 MOD_RES 1 1 N-acetylmethionine (Probable).
 MOD_RES 36 36 Phosphoserine; by PHK and PKC.
 DISULFID 3 51 Or C-51 with C-4 or C-9.  
Keyword
 Acetylation; Calmodulin-binding; Cell junction; Cell projection; Complete proteome; Cytoplasm; Direct protein sequencing; Disulfide bond; Phosphoprotein; Reference proteome; Synapse. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 78 AA 
Protein Sequence
MDCCTESACS KPDDDILDIP LDDPGANAAA AKIQASFRGH MARKKIKSGE CGRKGPGPGG 60
PGGAGGARGG AGGGPSGD 78 
Gene Ontology
 GO:0030054; C:cell junction; IEA:UniProtKB-KW.
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0043197; C:dendritic spine; IEA:UniProtKB-SubCell.
 GO:0045202; C:synapse; IEA:UniProtKB-SubCell. 
Interpro
 IPR000048; IQ_motif_EF-hand-BS. 
Pfam
 PF00612; IQ 
SMART
 SM00015; IQ 
PROSITE
 PS50096; IQ 
PRINTS