CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028279
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 DOMINA protein 
Protein Synonyms/Alias
 DOMINA protein (WHN-homologue); Jumeau; LD24749p; Winged-helix nude transcription factor; Winged-helix protein jumeaux 
Gene Name
 jumu 
Gene Synonyms/Alias
 Domina; Dwhn; CG4029; Dmel_CG4029 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
261NSLEELGKGKGSTLLacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; DNA-binding; Nucleus; Reference proteome; Transcription; Transcription regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 719 AA 
Protein Sequence
MFELEDYSSG IHEGFFSKYA DAAGPSLDFY VSDSMQEMLN VDIRAEIANV VGSSSSDLTS 60
SLDQTLEAIS AINNNQSNGN SSQSASYNAN ANFLTSSGLH ASPTAKWMGS SANFWSNSDY 120
YADLGACVNP ISVMPLINST SAGMFSPKKN KTASSTQGRS GAVPSSPSAE RDQHKSHLTF 180
SPAQMKVSAG SMRRDQVMAH IPKQISVVTG TGTTAPATMA TNSVLQRRNS SAVDAVRKDL 240
VTELRKAQSS PVPNSLEELG KGKGSTLLNA SVGATNTIKL APGIGGLTFA NSAAYQKLKQ 300
TSLVKSPGGI SPGAGSNMGL KREDSNKRGL QASTTPKSIA SAANSPHHQM QSNYSLGSPS 360
SLSSSSASSP LGNVSNLVNI ANNNTSGAGS GLVKPLQQKV KLPPVGSPFP KPAYSYSCLI 420
ALALKNSRAG SLPVSEIYSF LCQHFPYFEN APSGWKNSVR HNLSLNKCFE KIERPATNGN 480
QRKGCRWAMN PDRINKMDEE VQKWSRKDPA AIRGAMVYPQ HLESLERGEM KHGSADSDVE 540
LDSQSEIEES SDLEEHEFED TMVDAMLVEE EDEEEDGDDD EQIINDFDAE DERHANGNQA 600
NNLPINHPLL GQKSNDFDIE VGDLYDAIDI EDDKESVRRI ISNDQHIIEL NPADLNATDG 660
YNQQPALKRA RVDINYAIGP AGELEQQYGQ KVKVQQVIQP QQHPPTYNRR KMPLVNRVI 719 
Gene Ontology
 GO:0000791; C:euchromatin; IDA:FlyBase.
 GO:0005730; C:nucleolus; IDA:FlyBase.
 GO:0005701; C:polytene chromosome chromocenter; IDA:FlyBase.
 GO:0005667; C:transcription factor complex; IBA:RefGenome.
 GO:0008301; F:DNA binding, bending; IBA:RefGenome.
 GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.
 GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
 GO:0008134; F:transcription factor binding; IBA:RefGenome.
 GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IDA:FlyBase.
 GO:0008105; P:asymmetric protein localization; IMP:FlyBase.
 GO:0006325; P:chromatin organization; IMP:FlyBase.
 GO:0048749; P:compound eye development; IMP:FlyBase.
 GO:0050832; P:defense response to fungus; IMP:FlyBase.
 GO:0048813; P:dendrite morphogenesis; IMP:FlyBase.
 GO:0007391; P:dorsal closure; TAS:FlyBase.
 GO:0035050; P:embryonic heart tube development; IMP:FlyBase.
 GO:0007476; P:imaginal disc-derived wing morphogenesis; IMP:FlyBase.
 GO:0007517; P:muscle organ development; IMP:FlyBase.
 GO:0007400; P:neuroblast fate determination; IMP:FlyBase.
 GO:0007000; P:nucleolus organization; IMP:FlyBase.
 GO:0007389; P:pattern specification process; IBA:RefGenome.
 GO:0051302; P:regulation of cell division; IMP:FlyBase.
 GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome. 
Interpro
 IPR001766; TF_fork_head.
 IPR018122; TF_fork_head_CS.
 IPR011991; WHTH_DNA-bd_dom. 
Pfam
 PF00250; Fork_head 
SMART
 SM00339; FH 
PROSITE
 PS00658; FORK_HEAD_2
 PS50039; FORK_HEAD_3 
PRINTS
 PR00053; FORKHEAD.