CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-014843
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Secernin-1 
Protein Synonyms/Alias
  
Gene Name
 Scrn1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
349DRRHELYKAHEWARAacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 Regulates exocytosis in mast cells. Increases both the extent of secretion and the sensitivity of mast cells to stimulation with calcium (By similarity). 
Sequence Annotation
  
Keyword
 Complete proteome; Cytoplasm; Direct protein sequencing; Exocytosis; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 414 AA 
Protein Sequence
MSGAPPSYSF VALPPRAKDG LVVFGKNSAR PRDEVQEVVY FPAVDHEAES KVECTYISID 60
QVPRTHAIVI SRPAWLWGAE MGANEHGVCI ANEAINAREP AAETEALLGM DLVRLGLERG 120
TTAKEALDII VSLLDEHGQG GNYYEDAHSC HSFQSAYLLV DRDEAWVLET VGKYWAAERI 180
TEGVRCICNH LSLTTKMDEE HPELRTYAQS QGWWTGEDEF NFAQVFSPAD DHLDCCAGKD 240
SLEKQEESIT VQTMINILRD KASGVCIDSE SFLTTASIVS VLPQNRSSPC IHYFTGTPDP 300
SRSIFKPFIF VDDVKLVPKA QSPCFGDDDP AKKEPRFQEK PDRRHELYKA HEWARAVIES 360
DQEQGRTLRK TMLELEKQGL EAMEEILSSP EPPDPAEVGD LFYDCVDTEM KFFK 414 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0031965; C:nuclear membrane; IEA:Compara.
 GO:0016805; F:dipeptidase activity; IEA:InterPro.
 GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
 GO:0006508; P:proteolysis; IEA:InterPro. 
Interpro
 IPR005322; Peptidase_C69. 
Pfam
 PF03577; Peptidase_C69 
SMART
  
PROSITE
  
PRINTS