UniProt Accession

 B3KQF4_HUMAN; B3KQF4 

Genbank Protein ID

 AK074854 

Genbank Nucleotide ID

 BAG52016.1 

Protein Name

 cDNA FLJ90373 fis, clone NT2RP2004606, highly similar to Metalloproteinase inhibitor 1 

Protein Synonyms/Alias

  

Gene Name

  

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
45	SDLVIRAKFVGTPEV	ubiquitination	[1]

Reference

 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 

Functional Description

  

Sequence Annotation

  

Keyword

 Disulfide bond; Secreted. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 207 AA 

Protein Sequence

Gene Ontology

 GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
 GO:0008191; F:metalloendopeptidase inhibitor activity; IEA:InterPro. 

Interpro

 IPR001134; Netrin_domain.
 IPR001820; Prot_inh_TIMP.
 IPR008993; TIMP-like_OB-fold.
 IPR015611; TIMP1.
 IPR027465; TIMP_C_dom. 

Pfam

 PF00965; TIMP 

SMART

 SM00206; NTR 

PROSITE

 PS50189; NTR
 PS00288; TIMP 

PRINTS