CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036390
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Sorting nexin-14 
Protein Synonyms/Alias
  
Gene Name
 SNX14 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
359GPYIDVVKLQTMRCLubiquitination[1, 2]
560PDAQLPSKRIIGPKNubiquitination[1, 2]
566SKRIIGPKNYEFLKSubiquitination[2]
622LPDVNLGKIIKSVPGubiquitination[2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 833 AA 
Protein Sequence
MKMKTFVIIH FHLIQLGLQE LFPQGHSCAV CGKVKCKRHR PSLLLENYQP WLDLKISSKV 60
DASLSEVLEL VLENFVYPWY RDVTDDESFV DELRITLRFF ASVLIRRIHK VDIPSIITKK 120
LLKAAMKHIE VIVKARQKVK NTEFLQQAAL EEYGPELHVA LRSRRDELHY LRKLTELLFP 180
YILPPKATDC RSLTLLIREI LSGSVFLPSL DFLADPDTVN HLLIIFIDDS PPEKATEPAS 240
PLVPFLQKFA EPRNKKPSVL KLELKQIREQ QDLLFRFMNF LKQEGAVHVL QFCLTVEEFN 300
DRILRPELSN DEMLSLHEEL QKIYKTYCLD ESIDKIRFDP FIVEEIQRIA EGPYIDVVKL 360
QTMRCLFEAY EHVLSLLENV FTPMFCHSDE YFRQLLRGAE SPTRNSKLNR NTQKRGESFG 420
ISRIGSKIKG VFKSTTMEGA MLPNYGVAEG EDDFIEEGIV VMEDDSPVEA VSTPNTPRNL 480
AAWKISIPYV DFFEDPSSER KEKKERIPVF CIDVERNDRR AVGHEPEHWS VYRRYLEFYV 540
LESKLTEFHG AFPDAQLPSK RIIGPKNYEF LKSKREEFQE YLQKLLQHPE LSNSQLLADF 600
LSPNGGETQF LDKILPDVNL GKIIKSVPGK LMKEKGQHLE PFIMNFINSC ESPKPKPSRP 660
ELTILSPTSE NNKKLFNDLF KNNANRAENT ERKQNQNYFM EVMTVEGVYD YLMYVGRVVF 720
QVPDWLHHLL MGTRILFKNT LEMYTDYYLQ CKLEQLFQEH RLVSLITLLR DAIFCENTEP 780
RSLQDKQKGA KQTFEEMMNY IPDLLVKCIG EETKYESIRL LFDGLQQPVL NKQ 833 
Gene Ontology
 GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
 GO:0007154; P:cell communication; IEA:InterPro.
 GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro. 
Interpro
 IPR001683; Phox.
 IPR003114; Phox_assoc.
 IPR000342; Regulat_G_prot_signal.
 IPR016137; Regulat_G_prot_signal_superfam.
 IPR013937; Sorting_nexin_C. 
Pfam
 PF08628; Nexin_C
 PF00787; PX
 PF02194; PXA
 PF00615; RGS 
SMART
 SM00312; PX 
PROSITE
 PS50195; PX
 PS51207; PXA
 PS50132; RGS 
PRINTS