CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038312
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Nuclear factor of-activated T-cells 5 
Protein Synonyms/Alias
  
Gene Name
 Nfat5 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
140SNRGVSEKQLTGNTVacetylation[1]
Reference
 [1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Nucleus; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1552 AA 
Protein Sequence
MPSDFISLLS ADLDLESPKS LYSRDSLKLH PSQTFHRAGL LEESVYDLLP KELQLPPPRE 60
TSVASMSQTS GGEAGSPPPA VVAADASSAP SSSSMGGACS SFTTSSSPTI YSTSVTDSKA 120
MQVESCSSAV GVSNRGVSEK QLTGNTVQQH PSTPKRHTVL YISPPPEDLL DNSRMSCQDE 180
GCGLESEQSC SMWMEDSPSN FSNMSTSSYN DNTEVPRKSR KRNPKQRPGV KRRDCEESNM 240
DIFDADSAKA PHYVLSQLTT DNKGNSKAGN GTLDSQKGTG VKKSPMLCGQ YPVKSEGKEL 300
KIVVQPETQH RARYLTEGSR GSVKDRTQQG FPTVKLEGHN EPVVLQVFVG NDSGRVKPHG 360
FYQACRVTGR NTTPCKEVDI EGTTVIEVGL DPSNNMTLAV DCVGILKLRN ADVEARIGIA 420
GSKKKSTRAR LVFRVNITRK DGSTLTLQTP SSPILCTQPA GVPEILKKSL HSCSVKGEEE 480
VFLIGKNFLK GTKVIFQENV SDENSWKSEA EIDMELFHQN HLIVKVPPYH DQHITLPVSV 540
GIYVVTNAGR SHDVQPFTYT PDPAAGALNV NVKKEISSPA RPCSFEEAMK AMKTTGCNVD 600
KVTILPNALI TPLISSSMIK TEDVTPMEVT SEKRSSPIFQ TTKSIGSTQQ TLETISNIAG 660
GAPFSSPSSS SHLTPESENQ QQLQPKAYNP ETLTTIQTQD ISQPGTFPAV SAASQLPSSD 720
ALLQQATQFQ TREAQSRDTI QSDTVVNLSQ LTEASQQQQS PLQEQAQTLQ QQIPSNIFPS 780
PSSVSQLQST IQQLQAGSFT GSAAGGRSGS VDLVQQVLEA QQQLSSVLFS TPDGNENVQE 840
QLNADIFQVS QIQNSVSPGM FSSAESAVHT RPDNLLPGRA DSVHQQTENT LSNQQQQQQQ 900
QQQVMESSAA MVMEMQQSIC QAAAQIQSEL FPSAASASGS LQQSPVYQQP SHMMSALPTN 960
EDMQMQCELF SSPPAASGNE TSTTTTPQVA TPGSTMFQTP SSGDGEETGA QAKQIQNSVF 1020
QTMVQMQRSG DSQPQVNLFS STKNIMSVQN NGTQQQGNSL FQQGSEMMSL QSGNFLQQSS 1080
HSQAQLFHPQ NPIADAQNLS QETQGSIFHS PNPIVHSQTS TASSEQLQPS MFHSQNTIAV 1140
LQGSSVPQDQ QSPNIFLSQS SINNLQTNTV AQEEQISFFA AQNSISPLQS TSNTEQQAAF 1200
QQQPPISHIQ TPILSQEQAQ PSQQGLFQPQ VALGSLPPNP MPQNQQGPIF QTQRPIVGMQ 1260
SNSPSQEQQQ QQQQQQQQQQ QQQQQQQSIL FSNQNAMATM ASQKQPPPNM MFSPNQNPMA 1320
SQEQQNQSIF HQQSNMAPMN QEQQPMQFQN QPTVSSLQNP GPTQSESPQT SLFHSSPQIQ 1380
LVQGSPSSQD QQVTLFLSPA SMSALQTSIN QPDMQQSPLY SPQNNIPGIQ GSTSSPQPQA 1440
TLFHNTTGGT INQIQNSPGS SQQTSGMFLF GIQNNCSQLL TSGPATLPDQ LMAINQQGQP 1500
QNEGQSSVTT LLSQQMPETS PLASSVNSSQ NMEKIDLLVS LQSQGNNLTG SF 1552 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:MGI.
 GO:0005634; C:nucleus; IDA:MGI.
 GO:0003677; F:DNA binding; IDA:MGI.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:MGI.
 GO:0001816; P:cytokine production; IDA:MGI.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.
 GO:0070884; P:regulation of calcineurin-NFAT signaling cascade; IDA:MGI.
 GO:0006351; P:transcription, DNA-dependent; ISS:MGI. 
Interpro
 IPR013783; Ig-like_fold.
 IPR014756; Ig_E-set.
 IPR002909; IPT_TIG_rcpt.
 IPR008366; NFAT.
 IPR015646; NFAT5.
 IPR008967; p53-like_TF_DNA-bd.
 IPR011539; RHD. 
Pfam
 PF00554; RHD 
SMART
 SM00429; IPT 
PROSITE
 PS50254; REL_2 
PRINTS
 PR01789; NUCFACTORATC.