CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-003994
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Inositol-3-phosphate synthase 
Protein Synonyms/Alias
 MIP synthase; Myo-inositol 1-phosphate synthase; IPS; MI-1-P synthase 
Gene Name
 INO1 
Gene Synonyms/Alias
 YJL153C; J0610 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
13IAPITSVKVVTDKCTubiquitination[1]
101FQTKEGVKQPNYFGSubiquitination[1]
208NCINLDEKGNVTTRGubiquitination[1]
364GYNLSAPKQFRSKEIacetylation[2]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [2] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 
Functional Description
  
Sequence Annotation
 MOD_RES 368 368 Phosphoserine.  
Keyword
 3D-structure; Complete proteome; Cytoplasm; Direct protein sequencing; Inositol biosynthesis; Isomerase; Lipid biosynthesis; Lipid metabolism; NAD; Phospholipid biosynthesis; Phospholipid metabolism; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 533 AA 
Protein Sequence
MTEDNIAPIT SVKVVTDKCT YKDNELLTKY SYENAVVTKT ASGRFDVTPT VQDYVFKLDL 60
KKPEKLGIML IGLGGNNGST LVASVLANKH NVEFQTKEGV KQPNYFGSMT QCSTLKLGID 120
AEGNDVYAPF NSLLPMVSPN DFVVSGWDIN NADLYEAMQR SQVLEYDLQQ RLKAKMSLVK 180
PLPSIYYPDF IAANQDERAN NCINLDEKGN VTTRGKWTHL QRIRRDIQNF KEENALDKVI 240
VLWTANTERY VEVSPGVNDT MENLLQSIKN DHEEIAPSTI FAAASILEGV PYINGSPQNT 300
FVPGLVQLAE HEGTFIAGDD LKSGQTKLKS VLAQFLVDAG IKPVSIASYN HLGNNDGYNL 360
SAPKQFRSKE ISKSSVIDDI IASNDILYND KLGKKVDHCI VIKYMKPVGD SKVAMDEYYS 420
ELMLGGHNRI SIHNVCEDSL LATPLIIDLL VMTEFCTRVS YKKVDPVKED AGKFENFYPV 480
LTFLSYWLKA PLTRPGFHPV NGLNKQRTAL ENFLRLLIGL PSQNELRFEE RLL 533 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:UniProtKB.
 GO:0004512; F:inositol-3-phosphate synthase activity; IDA:UniProtKB.
 GO:0006021; P:inositol biosynthetic process; IDA:UniProtKB.
 GO:0008654; P:phospholipid biosynthetic process; IEA:UniProtKB-KW. 
Interpro
 IPR002587; Myo-inos-1-P_Synthase.
 IPR013021; Myo-inos-1-P_Synthase_GAPDH.
 IPR016040; NAD(P)-bd_dom. 
Pfam
 PF01658; Inos-1-P_synth
 PF07994; NAD_binding_5 
SMART
  
PROSITE
  
PRINTS