UniProt Accession

 CCD53_HUMAN; Q9Y3C0; B2RC74; Q53FF0; Q6IAI4; Q96QK0 

Genbank Protein ID

 AF155655; AF151874; CR457171; AK223339; AK314970; CH471054; BC010889 

Genbank Nucleotide ID

 AAF67012.1; AAD34111.1; CAG33452.1; BAD97059.1; BAG37471.1; EAW97687.1; AAH10889.1 

Protein Name

 WASH complex subunit CCDC53 

Protein Synonyms/Alias

 Coiled-coil domain-containing protein 53 

Gene Name

 CCDC53 

Gene Synonyms/Alias

 AD-016; CGI-116; x0009 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
24	KVPAIQQKRTVAFLN	ubiquitination	[1]
51	FSTVCEEKLADLSLR	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

 Component of the WASH complex, a complex present at the surface of endosomes that recruits and activates the Arp2/3 complex to induce actin polymerization. The WASH complex plays a key role in the fission of tubules that serve as transport intermediates during endosome sorting. 

Sequence Annotation

  

Keyword

 Coiled coil; Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 194 AA 

Protein Sequence

Gene Ontology

 GO:0071203; C:WASH complex; IDA:UniProtKB. 

Interpro

 IPR019309; WASH_CCDC53. 

Pfam

 PF10152; DUF2360 

SMART

  

PROSITE

  

PRINTS