CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-018231
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Stereocilin 
Protein Synonyms/Alias
  
Gene Name
 Strc 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
770WALRTLVKAYLRMPPacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 Essential to the formation of horizontal top connectors between outer hair cell stereocilia. 
Sequence Annotation
 CARBOHYD 63 63 N-linked (GlcNAc...) (Potential).
 CARBOHYD 200 200 N-linked (GlcNAc...) (Potential).
 CARBOHYD 295 295 N-linked (GlcNAc...) (Potential).
 CARBOHYD 352 352 N-linked (GlcNAc...) (Potential).
 CARBOHYD 364 364 N-linked (GlcNAc...) (Potential).
 CARBOHYD 467 467 N-linked (GlcNAc...) (Potential).
 CARBOHYD 516 516 N-linked (GlcNAc...) (Potential).
 CARBOHYD 580 580 N-linked (GlcNAc...) (Potential).
 CARBOHYD 605 605 N-linked (GlcNAc...) (Potential).
 CARBOHYD 696 696 N-linked (GlcNAc...) (Potential).
 CARBOHYD 860 860 N-linked (GlcNAc...) (Potential).
 CARBOHYD 952 952 N-linked (GlcNAc...) (Potential).
 CARBOHYD 1000 1000 N-linked (GlcNAc...) (Potential).
 CARBOHYD 1213 1213 N-linked (GlcNAc...) (Potential).
 CARBOHYD 1308 1308 N-linked (GlcNAc...) (Potential).  
Keyword
 Cell projection; Cilium; Complete proteome; Glycoprotein; Hearing; Reference proteome; Signal. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1809 AA 
Protein Sequence
MALSLQPQLL LLLSLLPQEV TSAPTGPQSL DAGLSLLKSF VATLDQAPQR SLSQSRFSAF 60
LANISSSFQL GRMGEGPVGE PPPLQPPALR LHDFLVTLRG SPDWEPMLGL LGDVLALLGQ 120
EQTPRDFLVH QAGVLGGLVE ALLGALVPGG PPAPTRPPCT RDGPSDCVLA ADWLPSLMLL 180
LEGTRWQALV QLQPSVDPTN ATGLDGREPA PHFLQGLLGL LTPAGELGSE EALWGGLLRT 240
VGAPLYAAFQ EGLLRVTHSL QDEVFSIMGQ PEPDASGQCQ GGNLQQLLLW GMRNNLSWDA 300
RALGFLSGSP PPPPALLHCL SRGVPLPRAS QPAAHISPRQ RRAISVEALC ENHSGPEPPY 360
SISNFSIYLL CQHIKPATPR PPPTTPRPPP TTPQPPPTTT QPIPDTTQPP PVTPRPPPTT 420
PQPPPSTAVI CQTAVWYAVS WAPGARGWLQ ACHDQFPDQF LDMICGNLSF SALSGPSRPL 480
VKQLCAGLLP PPTSCPPGLI PVPLTPEIFW GCFLENETLW AERLCVEDSL QAVPPRNQAW 540
VQHVCRGPTL DATDFPPCRV GPCGERCPDG GSFLLMVCAN DTLYEALVPF WAWLAGQCRI 600
SRGGNDTCFL EGMLGPLLPS LPPLGPSPLC LAPGPFLLGM LSQLPRCQSS VPALAHPTRL 660
HYLLRLLTFL LGPGTGGAET QGMLGQALLL SSLPDNCSFW DAFRPEGRRS VLRTVGEYLQ 720
REEPTPPGLD SSLSLGSGMS KMELLSCFSP VLWDLLQREK SVWALRTLVK AYLRMPPEDL 780
QQLVLSAEME AAQGFLTLML RSWAKLKVQP SEEQAMGRLT ALLLQRYPRL TSQLFIDMSP 840
LIPFLAVPDL MRFPPSLLAN DSVLAAIRDH SSGMKPEQKE ALAKRLLAPE LFGEVPDWPQ 900
ELLWAALPLL PHLPLESFLQ LSPHQIQALE DSWPVADLGP GHARHVLRSL VNQSMEDGEE 960
QVLRLGSLAC FLSPEELQSL VPLSDPMGPV EQGLLECAAN GTLSPEGRVA YELLGVLRSS 1020
GGTVLSPREL RVWAPLFPQL GLRFLQELSE TQLRAMLPAL QGASVTPAQA VLLFGRLLPK 1080
HDLSLEELCS LHPLLPGLSP QTLQAIPKRV LVGACSCLGP ELSRLSACQI AALLQTFRVK 1140
DGVKNMGAAG AGSAVCIPGQ PTTWPDCLLP LLPLKLLQLD AAALLANRRL YRQLPWSEQQ 1200
AQFLWKKMQV PTNLSLRNLQ ALGNLAGGMT CEFLQQISSM VDFLDVVHML YQLPTGVRES 1260
LRACIWTELQ RRMTMPEPEL TTLGPELSEL DTKLLLDLPI QLMDRLSNDS IMLVVEMVQG 1320
APEQLLALTP LHQTALAERA LKNLAPKETP ISKEVLETLG PLVGFLGIES TRRIPLPILL 1380
SHLSQLQGFC LGETFATELG WLLLQEPVLG KPELWSQDEI EQAGRLVFTL SAEAISSIPR 1440
EALGPETLER LLGKHQSWEQ SRVGHLCGES QLAHKKAALV AGIVHPAAEG LQEPVPNCAD 1500
IRGTFPAAWS ATQISEMELS DFEDCLSLFA GDPGLGPEEL RAAMGKAKQL WGPPRGFRPE 1560
QILQLGRLLI GLGERELQEL TLVDWGVLSS LGQIDGWSSM QLRAVVSSFL RQSGRHVSHL 1620
DFIYLTALGY TVCGLRPEEL QHISSWEFSQ AALFLGSLHL PCSEEQLEVL AYLLVLPGGF 1680
GPVSNWGPEI FTEIGTIAAG IPDLALSALL RGQIQGLTPL AISVIPAPKF AVVFNPIQLS 1740
SLTRGQAVAV TPEQLAYLSP EQRRAVAWAQ HEGKEIPEQL GRNSAWGLYD WFQASWALAL 1800
PVSIFGHLL 1809 
Gene Ontology
 GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.
 GO:0060091; C:kinocilium; IDA:UniProtKB.
 GO:0032420; C:stereocilium; IEA:UniProtKB-SubCell.
 GO:0032426; C:stereocilium bundle tip; IDA:UniProtKB.
 GO:0060088; P:auditory receptor cell stereocilium organization; IMP:UniProtKB.
 GO:0050910; P:detection of mechanical stimulus involved in sensory perception of sound; IMP:MGI. 
Interpro
 IPR026061; Stereocilin.
 IPR026664; Stereocilin_related. 
Pfam
  
SMART
  
PROSITE
  
PRINTS