CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-045218
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Neutral amino acid transporter B(0) 
Protein Synonyms/Alias
  
Gene Name
 SLC1A5 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
88VFGVALRKLGPEGELubiquitination[1, 2]
213EENNGVAKHISRFILubiquitination[1, 2, 3, 4]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [3] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [4] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 259 AA 
Protein Sequence
XHASLLGLKE ADSPSPAKGC KPSSNPAGLR NIFPSNLVSA AFRSYSTTYE ERNITGTRVK 60
VPVGQEVEGM NILGLVVFAI VFGVALRKLG PEGELLIRFF NSFNEATMVL VSWIMWYAPV 120
GIMFLVAGKI VEMEDVGLLF ARLGKYILCC LLGHAIHGLL VLPLIYFLFT RKNPYRFLWG 180
IVTPLATAFG TSSSSATLPL MMKCVEENNG VAKHISRFIL PIGATVNMDG AALFQCVAAV 240
FIAQLSQQSL DFVKIITIL 259 
Gene Ontology
 GO:0016020; C:membrane; IEA:InterPro.
 GO:0017153; F:sodium:dicarboxylate symporter activity; IEA:InterPro. 
Interpro
 IPR001991; Na-dicarboxylate_symporter.
 IPR018107; Na-dicarboxylate_symporter_CS. 
Pfam
 PF00375; SDF 
SMART
  
PROSITE
 PS00714; NA_DICARBOXYL_SYMP_2 
PRINTS
 PR00173; EDTRNSPORT.