| Tag | Content |
|---|
| CPLM ID | CPLM-037317 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Folliculin-interacting protein 1 |
Protein Synonyms/Alias | |
Gene Name | FNIP1 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 8 | MAPTLFQKLFSKRTG | ubiquitination | [1] | | 64 | VLFDSSVKRRNEDIS | ubiquitination | [1] | | 412 | MHGIVRTKVDDCQFV | ubiquitination | [1] | | 439 | HVEKNTHKVEEEGEI | ubiquitination | [1] | | 585 | WRQVVLQKASRESPL | ubiquitination | [1] | | 616 | EGVEPGSKAADSGLK | ubiquitination | [1] | | 623 | KAADSGLKRGDQIME | ubiquitination | [1] | | 867 | RLPDQFSKLADRIQL | ubiquitination | [1] | | 1433 | FQSLPNPKSWDFLNS | ubiquitination | [1] | | 1465 | SEPYSCSKSCSRTCG | ubiquitination | [1] | | 1475 | SRTCGQCKGSLERKS | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | |
Sequence Annotation | |
Keyword | Complete proteome; Guanine-nucleotide releasing factor; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1651 AA |
Protein Sequence | MAPTLFQKLF SKRTGLGAPG RDARDPDCGF SWPLPEFDPS QIRLIVYQDC ERRGRNVLFD 60
SSVKRRNEDI SVSDLNTIYS YLHGMEILSN LREHQLRLMS ARARYERYSG NQVLFCSETI 120
ARCWYILLSG SVLVKGSMVL PPCSFGKQFG GKRGCDCLVL EPSEMIVVEN AKDNEDSILQ 180
REIPARQSRR RFRKINYKGE RQTITDDVEV NSYLSLPADL TKMHLTENPH PQVTHVSSSQ 240
SGCSIASDSG SSSLSDIYQA TESEVGDVDL TRLPEGPVDS EDDEEEDEEI DRTDPLQGRD 300
LVRECLEKEP ADKTDDDIEQ LLEFMHQLPA FANMTMSVRR ELCSVMIFEV VEQAGAIILE 360
DGQELDSWYV ILNGTVEISH PDGKVENLFM GNSFGITPTL DKQYMHGIVR TKVDDCQFVC 420
IAQQDYWRIL NHVEKNTHKV EEEGEIVMVH EHRELDRSGT RKGHIVIKAT PERLIMHLIE 480
EHSIVDPTYI EDFLLTYRTF LESPLDVGIK LLEWFKIDSL RDKVTRIVLL WVNNHFNDFE 540
GDPAMTRFLE EFEKNLEDTK MNGHLRLLNI ACAAKAKWRQ VVLQKASRES PLQFSLNGGS 600
EKGFGIFVEG VEPGSKAADS GLKRGDQIME VNGQNFENIT FMKAVEILRN NTHLALTVKT 660
NIFVFKELLF RTEQEKSGVP HIPKIAEKKS NRHSIQHVPG DIEQTSQEKG SKKVKANTVS 720
GGRNKIRKIL DKTRFSILPP KLFSDGGLSQ SQDDSIVGTR HCRHSLAIMP IPGTLSSSSP 780
DLLQPTTSML DFSNPSDIPD QVIRVFKVDQ QSCYIIISKD TTAKEVVFHA VHEFGLTGAS 840
DTYSLCEVSV TPEGVIKQRR LPDQFSKLAD RIQLNGRYYL KNNMETETLC SDEDAQELVK 900
ESQLSMLQLS TIEVATQLSM RDFDLFRNIE PTEYIDDLFK LNSKTGNTHL KRFEDIVNQE 960
TFWVASEILT EANQLKRMKI IKHFIKIALH CRECKNFNSM FAIISGLNLA SVARLRGTWE 1020
KLPSKYEKHL QDLQDIFDPS RNMAKYRNIL SSQSMQPPII PLFPVVKKDM TFLHEGNDSK 1080
VDGLVNFEKL RMISKEIRQV VRMTSANMDP AMMFRQRSLS QGSTNSNMLD VQGGAHKKRA 1140
RRSSLLNAKK LYEDAQMARK VKQYLSSLDV ETDEEKFQMM SLQWEPAYGT LTKNLSEKRS 1200
AKSSEMSPVP MRSAGQTTKA HLHQPHRVSQ VLQVPAVNLH PIRKKGQTKD PALNTSLPQK 1260
VLGTTEEISG KKHTEDTISV ASSLHSSPPA SPQGSPHKGY TLIPSAKSDN LSDSSHSEIS 1320
SRSSIVSNCS VDSMSAALQD ERCSSQALAV PESTGALEKT EHASGIGDHS QHGPGWTLLK 1380
PSLIKCLAVS SSVSNEEISQ EHIIIEAADS GRGSWTSCSS SSHDNFQSLP NPKSWDFLNS 1440
YRHTHLDDPI AEVEPTDSEP YSCSKSCSRT CGQCKGSLER KSWTSSSSLS DTYEPNYGTV 1500
KQRVLESTPA ESSEGLDPKD ATDPVYKTVT SSTEKGLIVY CVTSPKKDDR YREPPPTPPG 1560
YLGISLADLK EGPHTHLKPP DYSVAVQRSK MMHNSLSRLP PASLSSNLVA CVPSKIVTQP 1620
QRHNLQPFHP KLGDVTDADS EADENEQVSA V 1651 |
Gene Ontology | GO:0005622; C:intracellular; IEA:InterPro. GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro. GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |