Tag | Content |
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CPLM ID | CPLM-014042 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Oligoribonuclease, mitochondrial |
Protein Synonyms/Alias | RNA exonuclease 2 homolog; Small fragment nuclease |
Gene Name | Rexo2 |
Gene Synonyms/Alias | Smfn |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
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148 | GNSVHADKKFLDKHM | acetylation | [1] | 153 | ADKKFLDKHMPQFMK | acetylation | [1] | 160 | KHMPQFMKHLHYRII | acetylation | [1] | 173 | IIDVSTVKELCRRWY | acetylation | [1] | 205 | DDISESIKELQFYRN | acetylation | [1] | 234 | IENGENEKPVS**** | acetylation | [1] |
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Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | 3'-to-5' exoribonuclease specific for small oligoribonucleotides. Active on small (primarily =5 nucleotides in length) single-stranded RNA and DNA oligomers. May have a role for cellular nucleotide recycling (By similarity). |
Sequence Annotation | DOMAIN 43 207 Exonuclease. MOD_RES 122 122 Phosphotyrosine (By similarity). MOD_RES 184 184 Phosphotyrosine (By similarity). |
Keyword | Complete proteome; Exonuclease; Hydrolase; Manganese; Mitochondrion; Nuclease; Phosphoprotein; Reference proteome; Transit peptide. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 237 AA |
Protein Sequence | MLGVSLGARL LRGVGGRRGQ FGARGVSEGS AAMAAGESMA QRMVWVDLEM TGLDIEKDQI 60 IEMACLITDS DLNILAEGPN LIIKQPDELL DSMSDWCKEH HGKSGLTKAV KESTVTLQQA 120 EYEFLSFVRQ QTPPGLCPLA GNSVHADKKF LDKHMPQFMK HLHYRIIDVS TVKELCRRWY 180 PEDYEFAPKK AASHRALDDI SESIKELQFY RNNIFKKKTD EKKRKIIENG ENEKPVS 237 |
Gene Ontology | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. GO:0005730; C:nucleolus; IEA:Compara. GO:0005886; C:plasma membrane; IEA:Compara. GO:0008408; F:3'-5' exonuclease activity; IEA:Compara. GO:0003676; F:nucleic acid binding; IEA:InterPro. GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; IEA:GOC. |
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PRINTS | |