CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-021253
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein ITFG3 
Protein Synonyms/Alias
  
Gene Name
 ITFG3 
Gene Synonyms/Alias
 C16orf9 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
5***MLDHKDLEAEIHubiquitination[1]
15EAEIHPLKNEERKSQubiquitination[2]
30ENLGNPSKNEDNVKSubiquitination[2]
365LTPRWTPKAAHVLRKubiquitination[3]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
 MOD_RES 21 21 Phosphoserine.
 CARBOHYD 116 116 N-linked (GlcNAc...) (Potential).
 CARBOHYD 314 314 N-linked (GlcNAc...).
 CARBOHYD 389 389 N-linked (GlcNAc...).
 CARBOHYD 473 473 N-linked (GlcNAc...).  
Keyword
 Alternative splicing; Complete proteome; Glycoprotein; Membrane; Phosphoprotein; Reference proteome; Signal-anchor; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 552 AA 
Protein Sequence
MLDHKDLEAE IHPLKNEERK SQENLGNPSK NEDNVKSAPP QSRLSRCRAA AFFLSLFLCL 60
FVVFVVSFVI PCPDRPASQR MWRIDYSAAV IYDFLAVDDI NGDRIQDVLF LYKNTNSSNN 120
FSRSCVDEGF SSPCTFAAAV SGANGSTLWE RPVAQDVALV ECAVPQPRGS EAPSACILVG 180
RPSSFIAVNL FTGETLWNHS SSFSGNASIL SPLLQVPDVD GDGAPDLLVL TQEREEVSGH 240
LYSGSTGHQI GLRGSLGVDG ESGFLLHVTR TGAHYILFPC ASSLCGCSVK GLYEKVTGSG 300
GPFKSDPHWE SMLNATTRRM LSHSSGAVRY LMHVPGNAGA DVLLVGSEAF VLLDGQELTP 360
RWTPKAAHVL RKPIFGRYKP DTLAVAVENG TGTDRQILFL DLGTGAVLCS LALPSLPGGP 420
LSASLPTADH RSAFFFWGLH ELGSTSETET GEARHSLYMF HPTLPRVLLE LANVSTHIVA 480
FDAVLFEPSR HAAYILLTGP ADSEAPGLVS VIKHKVRDLV PSSRVVRLGE GGPDSDQAIR 540
DRFSRLRYQS EA 552 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. 
Interpro
 IPR011047; Quinonprotein_ADH-like_supfam. 
Pfam
  
SMART
  
PROSITE
  
PRINTS